ID M6BUE7_LEPBO Unreviewed; 603 AA.
AC M6BUE7;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Transporter, CPA2 family {ECO:0000313|EMBL:EMJ77445.1};
GN ORFNames=LEP1GSC016_2814 {ECO:0000313|EMBL:EMJ77445.1};
OS Leptospira borgpetersenii serovar Hardjo-bovis str. Sponselee.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=1303729 {ECO:0000313|EMBL:EMJ77445.1, ECO:0000313|Proteomes:UP000011873};
RN [1] {ECO:0000313|EMBL:EMJ77445.1, ECO:0000313|Proteomes:UP000011873}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Sponselee CDC {ECO:0000313|EMBL:EMJ77445.1,
RC ECO:0000313|Proteomes:UP000011873};
RA Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA Sanka R., DePew J., Purushe J., Galloway R.L., Vinetz J.M., Sutton G.G.,
RA Nierman W.C., Fouts D.E.;
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2 (CPA2)
CC transporter (TC 2.A.37) family. {ECO:0000256|ARBA:ARBA00005551}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMJ77445.1}.
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DR EMBL; ANMU01000185; EMJ77445.1; -; Genomic_DNA.
DR RefSeq; WP_011669199.1; NZ_AQCK01000155.1.
DR AlphaFoldDB; M6BUE7; -.
DR PATRIC; fig|1218567.3.peg.4324; -.
DR Proteomes; UP000011873; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR004771; K/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003148; RCK_N.
DR NCBIfam; TIGR00932; 2a37; 1.
DR PANTHER; PTHR46157; K(+) EFFLUX ANTIPORTER 3, CHLOROPLASTIC; 1.
DR PANTHER; PTHR46157:SF4; K(+) EFFLUX ANTIPORTER 3, CHLOROPLASTIC; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR Pfam; PF02254; TrkA_N; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51201; RCK_N; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|ARBA:ARBA00022538};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 31..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 114..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 402..524
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
SQ SEQUENCE 603 AA; 66586 MW; 1125A80D2306CF8B CRC64;
MQDNLLVTLI VFLSAAVISV PFFKKIGLGS VVGYLIGGII IGPWGIGLIT NVDSILHISE
FGVILLLFLI GLELKPQRLW ILKKPIFGLG GLQVILTFFF FFTILSFLDM EKSQVIVISI
SISLSSTAFA LQLLGEKNEL KTMHGRSVFA ILLFQDLAVI PIMAILPFLT ESVADPGSQG
SIKQIAVATG TILTVILAGR FLARPLFKLV ASSGNHEIFT ALSLLIVIGV SLLMDQVGLS
MALGSFLGGV ILADSEYRHE LESNLEPFKG LFLGLFFLAV GMSINLSEVL KDPILVLFSA
LILILVKATV LFFIGKISNH SNETSLNLSV TIAQGGEFAF VILGVGVSLS ILPKERADLV
IAIVTLSMGL TPILGIFKDK IVELIFKKDQ NFKEDTIEEQ NRVIIAGFGR FGQIIARMLF
VHRIGFTALE HNPDQVNVAR KFGYKIYYGD ASKLSLLRSA GAEQADLFIL AIQDIDISIK
VAELIKKHFP NLTIISRARN REHVFKLMEL GIQIIRRDTF ASALELAGET LRKLGFMDSE
VEKKIKKFRA HDELTLKGQF QIRNDEKEFI KFSKNSMRQL EVAFEADRQE KEGKLSDQNL
SSL
//
