ID M6FKG9_9LEPT Unreviewed; 170 AA.
AC M6FKG9;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN ORFNames=LEP1GSC038_1163 {ECO:0000313|EMBL:EMM70624.1};
OS Leptospira weilii str. 2006001855.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=996804 {ECO:0000313|EMBL:EMM70624.1, ECO:0000313|Proteomes:UP000012101};
RN [1] {ECO:0000313|EMBL:EMM70624.1, ECO:0000313|Proteomes:UP000012101}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2006001855 {ECO:0000313|EMBL:EMM70624.1,
RC ECO:0000313|Proteomes:UP000012101};
RA Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA Sanka R., DePew J., Purushe J., Hospenthal D.R., Murray C.K., Pimentel G.,
RA Wasfy M., Vinetz J.M., Sutton G.G., Nierman W.C., Fouts D.E.;
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC Evidence={ECO:0000256|ARBA:ARBA00001279};
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMM70624.1}.
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DR EMBL; AFJM02000074; EMM70624.1; -; Genomic_DNA.
DR AlphaFoldDB; M6FKG9; -.
DR Proteomes; UP000012101; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR012327; MeTrfase_D12.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR30481; DNA ADENINE METHYLASE; 1.
DR PANTHER; PTHR30481:SF3; DNA ADENINE METHYLASE; 1.
DR Pfam; PF02086; MethyltransfD12; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:EMM70624.1};
KW Transferase {ECO:0000313|EMBL:EMM70624.1}.
SQ SEQUENCE 170 AA; 19256 MW; 355587C473C4A0F3 CRC64;
MFLSRSCYGG VVRFRKADGY MSTPCGIHNP LSPKSFAERV YSWSDRVADC EFFNLNYKDA
FDAAKADDLI YCDPPYKDSQ AILYGAQSFS LKDLYDSIEN AKLRGVKIAL SIDGSKKSGS
KIIDIQYPKE LFSSEIPILN GRSMLKRFQM AGQTLEEEIV TERLLLTYKI
//
