ID   M6G445_LEPIR            Unreviewed;       257 AA.
AC   M6G445;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   SubName: Full=Aromatic ring-opening dioxygenase, catalytic subunit LigB {ECO:0000313|EMBL:EMM79798.1};
GN   ORFNames=LEP1GSC037_5659 {ECO:0000313|EMBL:EMM79798.1};
OS   Leptospira interrogans str. 2006001854.
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptospira.
OX   NCBI_TaxID=1001590 {ECO:0000313|EMBL:EMM79798.1, ECO:0000313|Proteomes:UP000012128};
RN   [1] {ECO:0000313|EMBL:EMM79798.1, ECO:0000313|Proteomes:UP000012128}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2006001854 {ECO:0000313|EMBL:EMM79798.1,
RC   ECO:0000313|Proteomes:UP000012128};
RA   Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA   Sanka R., DePew J., Purushe J., Hospenthal D.R., Murray C.K., Pimentel G.,
RA   Wasfy M., Parker T., Miller R.S., Vinetz J.M., Sutton G.G., Nierman W.C.,
RA   Fouts D.E.;
RL   Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the DODA-type extradiol aromatic ring-opening
CC       dioxygenase family. {ECO:0000256|ARBA:ARBA00007581}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMM79798.1}.
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DR   EMBL; AFLW02000221; EMM79798.1; -; Genomic_DNA.
DR   AlphaFoldDB; M6G445; -.
DR   Proteomes; UP000012128; Unassembled WGS sequence.
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008198; F:ferrous iron binding; IEA:InterPro.
DR   GO; GO:0016701; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006725; P:cellular aromatic compound metabolic process; IEA:InterPro.
DR   CDD; cd07363; 45_DOPA_Dioxygenase; 1.
DR   Gene3D; 3.40.830.10; LigB-like; 1.
DR   InterPro; IPR014436; Extradiol_dOase_DODA.
DR   InterPro; IPR004183; Xdiol_dOase_suB.
DR   PANTHER; PTHR30096:SF0; 4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN; 1.
DR   PANTHER; PTHR30096; UNCHARACTERIZED; 1.
DR   Pfam; PF02900; LigB; 1.
DR   PIRSF; PIRSF006157; Doxgns_DODA; 1.
DR   SUPFAM; SSF53213; LigB-like; 1.
PE   3: Inferred from homology;
KW   Dioxygenase {ECO:0000313|EMBL:EMM79798.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          35..253
FT                   /note="Extradiol ring-cleavage dioxygenase class III enzyme
FT                   subunit B"
FT                   /evidence="ECO:0000259|Pfam:PF02900"
SQ   SEQUENCE   257 AA;  29397 MW;  51BBDB1F47E2378E CRC64;
     MTNPVLFLGH GSPMNLITTS DFTQNLETFG TTLSEIKNIL VISAHWKTRG TYVTVADPPE
     QIYDFYGFPQ ELYEVKYRPS GSTELAQQIQ KLVKTVDVWA TKDWGLDHGS WGVLYFLFRK
     ANFPVIQLSI DANCNPEKQY EIGKELRPLR EEGTLILGSG NIVHNLHKAD FYNLNATPTD
     WAIEFDEYMR QALESRNDKT ILDFQNKGEI AKLAAPSTEH LEPIFYVLGA MKPEEKVKFI
     HHSFQNRTVS MRSFTSV
//