ID M6HG45_LEPIR Unreviewed; 639 AA.
AC M6HG45;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN Name=fliD {ECO:0000313|EMBL:EMM96318.1};
GN ORFNames=LEP1GSC158_3190 {ECO:0000313|EMBL:EMM96318.1};
OS Leptospira interrogans serovar Zanoni str. LT2156.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=1001601 {ECO:0000313|EMBL:EMM96318.1, ECO:0000313|Proteomes:UP000012089};
RN [1] {ECO:0000313|EMBL:EMM96318.1, ECO:0000313|Proteomes:UP000012089}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2156 {ECO:0000313|EMBL:EMM96318.1,
RC ECO:0000313|Proteomes:UP000012089};
RA Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA Sanka R., DePew J., Purushe J., Tulsiani S.M., Graham G.C., Burns M.-A.,
RA Dohnt M.F., Smythe L.D., McKay D.B., Craig S.B., Vinetz J.M., Sutton G.G.,
RA Nierman W.C., Fouts D.E.;
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|RuleBase:RU362066}.
CC Periplasmic flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMM96318.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AFMF02000023; EMM96318.1; -; Genomic_DNA.
DR AlphaFoldDB; M6HG45; -.
DR Proteomes; UP000012089; Unassembled WGS sequence.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0055040; C:periplasmic flagellum; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:EMM96318.1};
KW Cilium {ECO:0000313|EMBL:EMM96318.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|RuleBase:RU362066};
KW Flagellum {ECO:0000313|EMBL:EMM96318.1};
KW Periplasm {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 11..108
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 363..623
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
FT COILED 580..607
FT /evidence="ECO:0000256|RuleBase:RU362066"
SQ SEQUENCE 639 AA; 69976 MW; 2CEF132F5FB3F003 CRC64;
MPAFTIPGLS SGQDTNLIVK KLVELEAKPI RRLEQQNSFN KAQSKAWNDL KTVTTDLQEK
TRALISFTAP FAMKSIVSEP EGIISGDASR SASSGKRRIE IKELATSHQI SGEKTDVNKQ
IPAGKFKIFS GDSEKEIEFS GGTIRDLASS IKVSAAGLVN TGLVKVDGDN YVLTLTATFS
GKDRKLKFED SNGVLQAANL VGATEPADPP KELNFLPEKD QIQIFQPEKY GISSDSKPVF
KEESGKKWME IASVTSFQFG IPTTEFKKNT KIELATSTEF APEEKIELGI LYKENDKEKM
IFETASKENG KVVLNLKNFP SGQKVHKILL ANSSGKTIIL DSFHIIIPGE FKGAKPSKEI
AEAKDAVFLV DGIEVNRPKN EGLTDVLDGV SLNLHKKTEG PVNIDIKTDS DKGIEMIKEF
VAAYNTVLKF SKESTAVDKN STVRDGKEEG GEIGQSFWEG KTKTGLLSGE HTVIRLIAGM
KTVASSSYPV SGENSVRMLS DIGINTGKVG SKWADIQDGF LILDEDKLRS KLAENPDSVR
NLFAIDTNSD ARMDTGVGVD LLEHIKPYTQ YAGGLVSGKV KMLEEQVADN NKKIKEFENH
LVSYEKKLKS KFLYMEQGVG KNKAVGAYLN NNLKGARNE
//
