ID M6JPP6_9LEPT Unreviewed; 279 AA.
AC M6JPP6;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=SCO1/SenC {ECO:0000313|EMBL:EMN23731.1};
GN ORFNames=LEP1GSC063_1448 {ECO:0000313|EMBL:EMN23731.1};
OS Leptospira santarosai serovar Arenal str. MAVJ 401.
OC Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC Leptospira.
OX NCBI_TaxID=1049976 {ECO:0000313|EMBL:EMN23731.1, ECO:0000313|Proteomes:UP000012106};
RN [1] {ECO:0000313|EMBL:EMN23731.1, ECO:0000313|Proteomes:UP000012106}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MAVJ 401 {ECO:0000313|EMBL:EMN23731.1,
RC ECO:0000313|Proteomes:UP000012106};
RA Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA Sanka R., DePew J., Purushe J., Hartskeerl R.A., Ahmed A.,
RA van der Linden H., Goris M.G.A., Vinetz J.M., Sutton G.G., Nierman W.C.,
RA Fouts D.E.;
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the SCO1/2 family.
CC {ECO:0000256|ARBA:ARBA00010996}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMN23731.1}.
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DR EMBL; AHMU02000001; EMN23731.1; -; Genomic_DNA.
DR RefSeq; WP_004469271.1; NZ_AHMU02000001.1.
DR AlphaFoldDB; M6JPP6; -.
DR Proteomes; UP000012106; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd02968; SCO; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR003782; SCO1/SenC.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR12151; ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER; 1.
DR PANTHER; PTHR12151:SF8; THIOREDOXIN DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02630; SCO1-SenC; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
PE 3: Inferred from homology;
KW Copper {ECO:0000256|PIRSR:PIRSR603782-1};
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR603782-2};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR603782-1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 246..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT BINDING 86
FT /ligand="Cu cation"
FT /ligand_id="ChEBI:CHEBI:23378"
FT /evidence="ECO:0000256|PIRSR:PIRSR603782-1"
FT BINDING 90
FT /ligand="Cu cation"
FT /ligand_id="ChEBI:CHEBI:23378"
FT /evidence="ECO:0000256|PIRSR:PIRSR603782-1"
FT BINDING 179
FT /ligand="Cu cation"
FT /ligand_id="ChEBI:CHEBI:23378"
FT /evidence="ECO:0000256|PIRSR:PIRSR603782-1"
FT DISULFID 86..90
FT /note="Redox-active"
FT /evidence="ECO:0000256|PIRSR:PIRSR603782-2"
SQ SEQUENCE 279 AA; 31879 MW; 18215B382C9D1A14 CRC64;
MVFKNSLITG IAFCLFTTSL LSYDPAVRFD KNEKPKELEG VGVQEKLGNQ LDLSLSFRDE
TGKLVLLSSF FKKDKPVLLS LVYYKCPTLC NFHLNGITDV LKKLSWEVGK EFEYVAVSFD
PKETFDLAHA KKNAYLKEYS RGDGQGWHFL TGNQKEIATL ADSVGFSYKW NPENEQWIHS
SVAYVITPSG KISRYLHGVT FDERTLKLSL LEASDGKIGD FADQFALFCF QFDPGKNTYT
LYAYNIMKLG GFFTLLIMAA FLIPFWIRHN RDSELIRKE
//
