ID   M6Y9X6_9LEPT            Unreviewed;       632 AA.
AC   M6Y9X6;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Adenylate/guanylate cyclase catalytic domain protein {ECO:0000313|EMBL:EMO88671.1};
GN   ORFNames=LEP1GSC024_4904 {ECO:0000313|EMBL:EMO88671.1};
OS   Leptospira noguchii str. 2001034031.
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptospira.
OX   NCBI_TaxID=1193053 {ECO:0000313|EMBL:EMO88671.1, ECO:0000313|Proteomes:UP000012138};
RN   [1] {ECO:0000313|EMBL:EMO88671.1, ECO:0000313|Proteomes:UP000012138}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2001034031 {ECO:0000313|EMBL:EMO88671.1,
RC   ECO:0000313|Proteomes:UP000012138};
RA   Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA   Sanka R., DePew J., Purushe J., Whelen A.C., Vinetz J.M., Sutton G.G.,
RA   Nierman W.C., Fouts D.E.;
RL   Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMO88671.1}.
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DR   EMBL; AKXB02000121; EMO88671.1; -; Genomic_DNA.
DR   RefSeq; WP_004446603.1; NZ_AKXB02000121.1.
DR   AlphaFoldDB; M6Y9X6; -.
DR   Proteomes; UP000012138; Unassembled WGS sequence.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR045983; GUC-dom-containing_N.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR   Pfam; PF19363; DUF5939; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
FT   DOMAIN          461..575
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   632 AA;  73142 MW;  F341274066E1DA65 CRC64;
     METNQNKVKA SEILDLADFL KRFPWTGEWK VFKNPIETLW EFELDVEIET LWPWLIDTSS
     FNKRIGIPEM KFVEKEGKLF GRSKNAGILM EWEEVPWEWE YCKGLNNARI YSKGLARYVQ
     TRYELEKMPE NKTKLIVYFG WIPRGILGRI ILKFGMKQMY KNYQKGLAGL LDDIETKKKN
     ESIFNLNKSL RNSYSNADSL KLKQIKNNLL RERIEEALID RVVNYVLTED ENELYRIRIK
     KLAYEWKIPL ENILILFLHG CRQGLFTLSW DIICPHCRGV RSELSNLGDV PSQDSCDVCG
     IDFESTKLNT IEVTFHVHPS IREIQKRYFC AAEPATKTHI RFQRTVPPNS EYITNLLLND
     GVFRLRVSGE KKYNLLELQT SSSETFRWSA DQKGQELSAK PMPTVQILNT EKSPRIFIIE
     ERKEDSISLR PVELFNFQDF RDLFSEQAIA SNLQLDIGVQ TILFTDIVGS TRFYLTEGDN
     GAFKEIREHF VQAFRIIKEH KGAVVKTIGD AVMTSFSSPL DSLLASIQLQ KTFQITPENR
     IQIRISIHSG QCLAVNLNSN IDYFGNTVNY ASKLQGITEA GEIVFSEAIF RDGEIRNHLK
     TAGLKVKKVP FKLPWSQEED PAYKLIFNVS ST
//