ID M7AEI8_9ACTN Unreviewed; 253 AA.
AC M7AEI8;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=IclR family transcriptional regulator {ECO:0000313|EMBL:EMP15132.1};
GN ORFNames=ISGA_363 {ECO:0000313|EMBL:EMP15132.1};
OS Gordonia sp. NB41Y.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=875808 {ECO:0000313|EMBL:EMP15132.1, ECO:0000313|Proteomes:UP000011989};
RN [1] {ECO:0000313|EMBL:EMP15132.1, ECO:0000313|Proteomes:UP000011989}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NB4-1Y {ECO:0000313|EMBL:EMP15132.1,
RC ECO:0000313|Proteomes:UP000011989};
RX PubMed=23744905; DOI=10.1099/mic.0.068932-0;
RA Van Hamme J.D., Bottos E.M., Bilbey N.J., Brewer S.E.;
RT "Genomic and proteomic characterization of Gordonia sp. NB4-1Y in relation
RT to 6 : 2 fluorotelomer sulfonate biodegradation.";
RL Microbiology 159:1618-1628(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMP15132.1}.
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DR EMBL; APHK02000022; EMP15132.1; -; Genomic_DNA.
DR RefSeq; WP_020789683.1; NZ_CP132196.1.
DR AlphaFoldDB; M7AEI8; -.
DR STRING; 1241906.ISGA_363; -.
DR PATRIC; fig|1241906.3.peg.254; -.
DR OrthoDB; 60629at2; -.
DR Proteomes; UP000011989; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF24; HTH-TYPE TRANSCRIPTIONAL REPRESSOR ALLR; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011989};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 8..68
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 69..247
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
SQ SEQUENCE 253 AA; 26953 MW; C04408BE24725F3A CRC64;
MPRVSTGESV FARVVRIVEA FGIDDDALTV GEIARRSGLH VATASRLIGE LVGAGWLERD
HGSVRIGVRF WELASRASPA VGLREAAMPF MEDLRHVIGN DIQLAVREGV EVLILERLTS
PSPVVNYSRI AGRLPLHASS SGLVLLAYAG PELEAVVTAE PLTTYTPQTI RTPDQLRVAL
AHVRREGYAL CAGHIHPQTT GIAAPIRGRD GAVVAALGLI VPNDESAFGR IPALRAAARG
ISRVMARDDA ASK
//
