ID M7AN98_CHEMY Unreviewed; 240 AA.
AC M7AN98;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Hydroxysteroid 11-beta-dehydrogenase 1-like protein {ECO:0000256|ARBA:ARBA00040597};
DE AltName: Full=11-beta-hydroxysteroid dehydrogenase type 3 {ECO:0000256|ARBA:ARBA00042169};
GN ORFNames=UY3_18842 {ECO:0000313|EMBL:EMP24205.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP24205.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|ARBA:ARBA00006484}.
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DR EMBL; KB603100; EMP24205.1; -; Genomic_DNA.
DR AlphaFoldDB; M7AN98; -.
DR STRING; 8469.M7AN98; -.
DR eggNOG; KOG1205; Eukaryota.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR44279; HYDROXYSTEROID (11-BETA) DEHYDROGENASE 1-LIKE B-RELATED; 1.
DR PANTHER; PTHR44279:SF3; HYDROXYSTEROID 11-BETA-DEHYDROGENASE 1-LIKE PROTEIN; 1.
DR Pfam; PF00106; adh_short; 1.
DR PRINTS; PR00081; GDHRDH.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00061; ADH_SHORT; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000031443};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
SQ SEQUENCE 240 AA; 26835 MW; 01C1734E2CD3EC2C CRC64;
MAYHYSRFGA EIVLTARRGT LLQKVMEKCL QLGAKQVFYI QADMSSPQAP EKVVQFALQK
LGGLDHLVLN HIGGTPFRMW DGDVEHTRWL MQVNFLSYVA LASAALPILA ESKGSLIVVS
SLTGKISTPF TTSYSATKFA LDGFFSSLRH ELAMQKQDVC ITLCILGLID TEMALEKTRG
KVYMSAYPAA EAALAIIKGG ATRAREVFYP WWLELLCCLR DWFPNQRDVV IQSFYNYTSA
//
