ID M7AR28_CHEMY Unreviewed; 541 AA.
AC M7AR28;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Cytochrome P450 2G1 {ECO:0000313|EMBL:EMP25280.1};
GN ORFNames=UY3_17651 {ECO:0000313|EMBL:EMP25280.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP25280.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR EMBL; KB592215; EMP25280.1; -; Genomic_DNA.
DR AlphaFoldDB; M7AR28; -.
DR STRING; 8469.M7AR28; -.
DR eggNOG; KOG0156; Eukaryota.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
DR CDD; cd11026; CYP2; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR008067; Cyt_P450_E_grp-I_CYP2A-like.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24300:SF384; CYTOCHROME P450; 1.
DR PANTHER; PTHR24300; CYTOCHROME P450 508A4-RELATED; 1.
DR Pfam; PF00067; p450; 2.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR01684; EP450ICYP2A.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|RuleBase:RU000461};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU000461};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW Reference proteome {ECO:0000313|Proteomes:UP000031443};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 541 AA; 60821 MW; B52766C5BF513A62 CRC64;
MELEGSATLV LAAGILCLAL LWEWKQQQQS RKFPPGPTPL PLLGNALQLS RGDLFTSLMA
LRDQYGPVFT VLLGPRRVVV LCGYEAVKEA LVDHAEEFSG RGGMPSLDRI FHGYGVILAN
GERWRQLRQF SVATLRSLGM GKRTLEERIA EEARCLVEEI RKTRGSPFNP SLPVSHAVAN
VISSIAFGDR FDYQDPTFLS LLDVIQSLFL ELTSPWTRLY EMFPGIMRFL PGPHNRILKH
VDVLHNFVTE RVQRNQKTLD PGCPRDYIDA FLIKMEEEKQ NPLSEFHTKN LVLSVVHLFF
GGTEMVSSTL RYGFLLLMKY PEVQERVHQE IDGVIGRNRS PAAEDRSRMP YTHAVLHEIQ
RFSNIIPLGI PHAVIRDTQF QGYMLPKCTE AKESSDFKPS PSRLASRFAQ AMPASHMLCG
AALLTLAPGE KAKQGTDVFC MLGSALRDPR HFSDPERFNP GNFLDENGGF KKNHAFVAFS
SGKRVCLGEG LARMELFLVF TSVLQHFTLQ SPVDPQEIDL APKASGFWNI PPEYRVCALP
R
//
