ID M7AUF3_CHEMY Unreviewed; 962 AA.
AC M7AUF3;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Sorting nexin-13 {ECO:0000313|EMBL:EMP26615.1};
DE Flags: Fragment;
GN ORFNames=UY3_16301 {ECO:0000313|EMBL:EMP26615.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP26615.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB577554; EMP26615.1; -; Genomic_DNA.
DR AlphaFoldDB; M7AUF3; -.
DR STRING; 8469.M7AUF3; -.
DR eggNOG; KOG2101; Eukaryota.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd06873; PX_SNX13; 1.
DR CDD; cd08719; RGS_SNX13; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR037437; SNX13_PX.
DR InterPro; IPR037896; SNX13_RGS.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF3; SORTING NEXIN-13; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000031443};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 34..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 102..289
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 378..501
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 564..685
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EMP26615.1"
FT NON_TER 962
FT /evidence="ECO:0000313|EMBL:EMP26615.1"
SQ SEQUENCE 962 AA; 111580 MW; 3A12A49885D3F4E6 CRC64;
LFLFCFLFQT SLSIWGWGSL GVVLFLVTFG PFAIFYFAFY ILCFVGGGFV VTLLFGKTNS
EKYLEQCEHS FLPPTSVGVF KCTEEMKCEA RPIKIDRRLT GANIIDEPLQ QVIQFSLRDY
VQYWYYTLSD DESFLLEIRQ ALQNALIQFS TRSKEMDWQP YFTTRLVDDF ATHLRVFRKA
QQRITEKDDQ MKGTAEDLVD TFFKVEVEME KEVCRDLVCT SSKDEEGFLR DLCEVLLYLL
LPPGDFQNKI MRYFVREILA RGILLPLINQ LSDPDYINQY VIWMIRDSNC NYEAFMNVIK
LSDNVGELEA VRDKAGEELQ YLRSLDTAGD DINTIKNQIN SLLYVVKVCD SRIQRLQSGK
EIDTVKLAAN FGKLCTVPLD NILVDNVALQ FFMDYMQQTG GQAHLFFWMT VEGYRVTAQQ
QLEVLLSRQR DGKHQTNQTK GLLRAAAVGI YEQYLSEKAS PRVNIDDSLV AKLAETLNHE
EPTPEIFDDI QRKVYELMLR DERFYPSFKQ NALYVRMLAE LDMLKDPSFR GSDDGDGESF
NGSPTSSINL SLDDLSNVSS EESAQLHAYI SDTGVCNDHG KTYALYAITV HRRNPTSEEI
WKTYRRYSDF HDFHMRITEQ FENLASILKL PGKKTFNNMD REFLEKRKKD LNAYLQLLLN
PEMIKASPAL AHCVYDFLEN KAYSKGKGDF ARKMDTFVNP LRNSMRNVSN AVKSLPDSLA
EGMTKMSDNM GKMSERLGQD IKQSFFKVPP LMQKTDSDPE HCRVAAQLDD NVDDNIPLRV
MLLLMDEVFD LKERNQWLRR NIKNLLQQLI RATYGDTINR KIVDHVDSMT SPDQVADAVK
RFRDAFWPNG ILAETVPRRD KDIRMRTRVA GKTKLLEIMP DELKHIIGAE TTRKGILRVF
EMFQHTQLNK RMVYVFLEGF LETLFPQYKF HELFSKLHSR SEQMQRYKQR LQSTQAPSLQ
KR
//
