ID M7AY22_CHEMY Unreviewed; 495 AA.
AC M7AY22;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Heterogeneous nuclear ribonucleoprotein H {ECO:0000313|EMBL:EMP24678.1};
GN ORFNames=UY3_18225 {ECO:0000313|EMBL:EMP24678.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP24678.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleoplasm
CC {ECO:0000256|ARBA:ARBA00004642}.
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DR EMBL; KB598657; EMP24678.1; -; Genomic_DNA.
DR AlphaFoldDB; M7AY22; -.
DR STRING; 8469.M7AY22; -.
DR eggNOG; KOG4211; Eukaryota.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12729; RRM1_hnRNPH_hnRNPH2_hnRNPF; 1.
DR CDD; cd12731; RRM2_hnRNPH_hnRNPH2_hnRNPF; 1.
DR CDD; cd12734; RRM3_hnRNPH_hnRNPH2_hnRNPF; 1.
DR Gene3D; 3.30.70.330; -; 3.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR012996; Znf_CHHC.
DR PANTHER; PTHR13976:SF60; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H; 1.
DR PANTHER; PTHR13976; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED; 1.
DR Pfam; PF00076; RRM_1; 3.
DR Pfam; PF08080; zf-RNPHF; 1.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR PROSITE; PS50102; RRM; 3.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW Reference proteome {ECO:0000313|Proteomes:UP000031443};
KW Ribonucleoprotein {ECO:0000313|EMBL:EMP24678.1};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 65..144
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 165..242
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 336..411
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..51
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 495 AA; 53942 MW; B38BDA2C2CD1A254 CRC64;
MDPLRSEETE GEIPGLDVNA EPDDLARENL IQSQGMTSVD AATEGESEPS LASSMMLNTE
GGEGFVVKVR GLPWSCSAEE VQRFFSECKI QNGASGIRFI YTREGRPSGE AFVELETEDD
VKLALKKDRE TMGHRYVEVF KSNNVEMDWV LKHTGPNSPD TANDGFVRLR GLPFGCSKEE
IVQFFSGLEI VPNGITLPVD FQGRSTGEAF VQFASQEIAE KALKKHKERI GHRYIEIFKS
SRAEVRTHYD PPRKLLAMQR PGPYDRPGVG RGYNSLGRGS GFERMRRGAY GGGYGGYDDY
NGYSDGYGFG SDRFGRGMSD HRYGDASSTF QSTTGHCVHM RGLPYRATEN DIYNFFSPLN
PVRVHIEIGP DGRVTGEADV EFATHEDAVA AMSKDKANMQ HRYVELFLNS TAGGSGGAYG
SQMMGAMGNQ STYGANQQLS GGYGAGYGTQ SSMSGYGNQS AMNSSYYSSG NRASMGVNGM
GGMSNMSNMS AGWGM
//
