ID M7B2C9_CHEMY Unreviewed; 822 AA.
AC M7B2C9;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Inner centromere protein {ECO:0000313|EMBL:EMP32031.1};
DE Flags: Fragment;
GN ORFNames=UY3_10838 {ECO:0000313|EMBL:EMP32031.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP32031.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, spindle
CC {ECO:0000256|ARBA:ARBA00004186}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the INCENP family.
CC {ECO:0000256|ARBA:ARBA00010042}.
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DR EMBL; KB542907; EMP32031.1; -; Genomic_DNA.
DR AlphaFoldDB; M7B2C9; -.
DR STRING; 8469.M7B2C9; -.
DR eggNOG; KOG4456; Eukaryota.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR Gene3D; 6.10.250.2990; -; 1.
DR InterPro; IPR005635; Inner_centromere_prot_ARK-bd.
DR PANTHER; PTHR13142; INNER CENTROMERE PROTEIN; 1.
DR PANTHER; PTHR13142:SF1; INNER CENTROMERE PROTEIN; 1.
DR Pfam; PF03941; INCENP_ARK-bind; 1.
PE 3: Inferred from homology;
KW Chromosome partition {ECO:0000256|ARBA:ARBA00022829};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000031443}.
FT DOMAIN 729..785
FT /note="Inner centromere protein ARK-binding"
FT /evidence="ECO:0000259|Pfam:PF03941"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 168..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 307..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 341..404
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 425..483
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 505..744
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..34
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..50
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..211
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..240
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 351..381
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 425..439
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..483
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 505..683
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 684..711
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EMP32031.1"
SQ SEQUENCE 822 AA; 94254 MW; E7682DD43DE48FBB CRC64;
SDEPELMPKT PSQKNRPKRR LSSVQDENKD PIRKRLSRRS IKRASAKRCS RRLRSKEDLE
IIRAVVEEAS PPRRVTRSRA VVPDMHSVAL PEKSAVQPVE GRIPLVDISV NDRNSAELHL
KRSLPKTGAE VSKVIVLSSD DDSPKKAGMV ELQPMSAVSV LLIPETTKPK GEREGRSASK
LKIANTATRK ATVNREPAAE EMEDNQGSVK ELFQDLKDGT GTPTGSRSSR HSVRRSLMCR
SSMSCRTSLA EKYSLASKRE SMIRKSVSRT RSKRIAARQS SLASNCLIRH SSVESLMDEE
KTVKVRSELE STIPCKEGPQ GPRMSLRSRN AKTAVGNLVQ AEQQEGSGTE SQSDKSDEAQ
EQPQSVRRKP SYKKAVDELY DGQQAEEGGL SPPRKKTPSP LCPASKVVRP FKTFLHTVQK
NQLLMTPGSV GQSSKKKSFL KHNTPLRTDP KEKERQRLES LRKKQEAEQQ RKQKLEEEKR
QRLEEMKLKR EARLRKVLQA RERVEQLEEE KKRRIEQKLA QFDEKSEKVR EERLAEEKVK
KKVAAKKMGD VEARRRQEEE ARKQKALQLE EEERRHKERM QKKREEEEQE RAKKIAEQRQ
AEQEREKQLA AERELEKKKE QERIQAERER ERQEKEKAAR LQRELMAARE KERLQKEMEE
KEKKRQEEQR LAELERQEQE KKATAAASNH LNVTVDVENS PVCNSYQMTP QGPKGPKPPT
INPNNYGMDL NSDDSTDDES QPRKPIPAWA NGTQLSQAVI HQYYNPPDVT TLFGAIISPK
LENIFYKNKP RYFKRTSSAV WNSPPFPGAK AVLGLPYSLK KY
//
