ID M7B4I5_CHEMY Unreviewed; 2799 AA.
AC M7B4I5;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Protein prune homolog 2 {ECO:0000256|ARBA:ARBA00039860};
DE AltName: Full=BNIP2 motif-containing molecule at the C-terminal region 1 {ECO:0000256|ARBA:ARBA00042084};
GN ORFNames=UY3_12421 {ECO:0000313|EMBL:EMP30420.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP30420.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
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DR EMBL; KB549795; EMP30420.1; -; Genomic_DNA.
DR STRING; 8469.M7B4I5; -.
DR eggNOG; KOG4129; Eukaryota.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR InterPro; IPR022181; Bcl2-/adenovirus-E1B.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR PANTHER; PTHR12112; BNIP - RELATED; 1.
DR PANTHER; PTHR12112:SF11; PROTEIN PRUNE HOMOLOG 2; 1.
DR Pfam; PF12496; BNIP2; 1.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
PE 4: Predicted;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Reference proteome {ECO:0000313|Proteomes:UP000031443}.
FT DOMAIN 2572..2733
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000259|PROSITE:PS50191"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 97..131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 213..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 888..908
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 923..959
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 975..1039
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1127..1153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1207..1229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1259..1282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1299..1322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1804..1836
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2010..2189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2279..2330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2453..2474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2492..2513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..27
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..234
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 888..905
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 924..950
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 975..1003
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1012..1039
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1263..1282
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2026..2051
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2140..2177
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2296..2328
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2498..2513
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2799 AA; 311627 MW; 1394363E99F2F91B CRC64;
MVPNSRTSST EAVAGSAPLS QGSSGIMELY GSDIEPQPSS VNFIENPQDL NGSIQAHVDV
NIDLVSPDSG LATIRSSRSS KESSVFLSDD SPVAEGAHHS LLPGFDSYSP IPEGAIPEEQ
QPQSRNNSDN FDLFSFDLAP MVTIRSESSS RSVDYSPADD FFLNSDSSEG QPPIVQKELD
ETNLSENDMA NYSSNLLMTT NEEDSLVEFD DEFRQENPGD LSEKTSSLTD LVEDDSSSPE
VLKNVETRIP PTPMNSLVES SPLDNGPPLF FPQDVIKKIN EIDSASYSQS RARYGSWWDG
FELDSKNADA WSSSEQESVF QSPDSWKDRK ASPLLREHFD RRASDSVFLQ KQPRQMEYSR
TGLWENQFNS VRDKHSLELQ KKTTEHSHGQ STSLEETKQH MEAFTDLWKS SQLTPVISAP
WCNTVGESGQ LDAESYDVWT EFDQEDGAKP SENVWSMLKL DTDQTSVRSL EAWAMSKTNL
SYSSENTAEN ESENLNNEVS SEAWNKGRAY PVEEYSTFEN TKSSIDNVQN NSNLAVENQN
VLGDTKCRPK QFENMDVWDL YEKDIEKEVL ETLVPWEDSV LSYRCSDFSS SNAGEDLVVS
PPDTNYSTSD SYISPTFIGD ERENEDKHFD RETIFDEVIN SNSDEPKILE ETDKESLPQP
SIRSMPFLSS GNTEMWNVSL NNVSQLKAEN SEITALPNTC TVSRNSEQIA AKYFSGDENI
SESNSSSEDT GVMQVYNQTV NHLSQPHGGL NTRPTAAEKN VEIWNRVILE DTQSSTSTSE
MGNGFDLKGS DLENEVSVNG QVQGSINEDS ELRTQLSEQQ LNLWSVYLQQ NHQAGWENNG
ISGTSQQGID EYKRIDEMSG QLTISNVWNT TMQDNRVSPS VLSKLSCITN SEESTPPSEI
PNSPEKIRNS DIFKALETEK SEINMPFSCP SNPANQEQRK RTLQNNAESS ATSHEEERHS
GHLDFYNLQN YSHSNISQTL PRNTNKESTA TEGATSPEMK SASESYNKGE DGQENHSPTV
PENLDSWNDS AKSSSQSVVS SPLINEALEV FRGAQESLSE EVPSNLEICS FELGFSELSP
EISDAHETPF MSEILQTKIQ VNPSSESAEV PGITNISVMD NSLSHEMDSG GNDASEGLES
GNKIPDEEHV DTTSHHDFPQ ILGVWNSRMC EDTQSPGTSP ETSEVPEMTN TMNSLLGDTQ
IKSDCEEDNV WSGSTNDYTQ SSATSPDISD ASENVHVWGS MPATCHRESE DIWNITNDGL
EKAPEKGGFE NKSQGESEES IDHKVPKNLD LWNAHVDDDT VSSLSSPEAN EDSKNSEAPQ
AVIEIDSNYQ ANENKVSETK EHDYAQSSAV SSEDSLDAET ELEKEVQMAI LNKNSENVKP
WNISKEDDIM HLNTTNNDTC EAFEYLDGWE TSQGEFQVNT FQENPDHPHV WNSCTMDYYI
APSSAAGHKE YSSKNSESWN ISLQADSEIN QRSTVETNDH SEWWNSETHK HKPVEGQYSN
SDGGLEINQL ANIKLDAWGA PVQSEELKVA YPAYLGIHAN QSPPLYFKEE KYESIVHSRN
IHKSQIDPDI VQHKLSDPLA LAKKERDLKE QPFVTVDGDQ DTSKNAFPEK WQPDMPNTFA
QANLILDLSR DNVDVQIKTS SKDLFVQEQW NTGGTLEFCS SPKNAFIAND SSQKLIEKSS
LRWNELAEVR QITCSPYTLQ DETPESNQLF PVDPDLWTDT EQLFILKADG ENPDILSHCD
QDSSSLASNR PDVCHEYEAK HASSQSTDAL AEAGEVTQLV LTVSNISKEA DFDFKQQLVT
HKVETYPDRN SPENNDGTQV DQLISPKAHE GSEFRKENIL KKSDLEKKPV VELMDSAGSS
AEDLGMVSLH LKDACYENNI LAASVKVVHS QRHLVATDFF PLDNSEESIK DMSVSAETGQ
IPAIDHTAVT SDKVEISDMC VDGNETGIEN SSNTSITNSQ SLGEVSKLTI LNSKDNVAVE
RDATDEQTLF LKTSLDDNDR DAAVCQHADN VVKEPEHLPD SHNPWFKESP NEQSPVVYSS
PSDVSFNTEA TGSKERGKEI SLKQQFSGSV SVEMPLSPLP PQKDKMNFLE TKDSIAKDQS
FDSFAECPQE DQALGSLPLE SEVMPESSDI LKGLEHEAQR SNTDSPAGGV TGSPNEAASD
PLYTEGNGRN STESPELIST ESKEDMRTQV NKDQTALEMD YILVTAEENG SVKKDILETK
ESDFAFQEAN VAEQTESHEA FSAGFSDTFQ SISIINESKD QSFLTTEWGS FHLAEKSPSV
LPQRLGDEKR SPESPAQDHS WTVLGKNEAS DISPEEISSR TETMDSGSGH SVKELEAVLD
QELIHDKQSG VQLKKTPHKS FEQEKYSPLD SLTREDKNSS IVRTDALLLQ VVGGHGIWEV
HSQQHPGDGM ATEQEMEEET EFLNSERELN RVSGLVPEDV GMEIPFEEGV LSPDTTEIRP
EPPNSLDLNG SHPRRIKLTA PNINLSLDRS EGSVLSDDNL DTPDEIDINV DDLDTPDEAD
SFEYTGNEDQ AAVRDVFQEE SESIPEYTAE EERQDNRLWR TVVIGEQEQR IDMKVIEPYK
KVISHGGYYG DGLNAIIVFA ACFLPDSSRA DYNYVMENLF LYVISTLELM VAEDYMIVYL
NGATPRRKMP GFGWMKKCYQ MIDRRLRKNL KSFIIVHPSW FIRTILAVTR PFISSKFSSK
IQYVGTLAEL SELIPMEYVH IPESIVKTDS FSHHTPRRIN KMTQLVAVSR STGDAPEVLA
PHMSPKSDCR PPPCHLLCTY FLALRNPPLT PAQMGSIFN
//
