ID M7B540_CHEMY Unreviewed; 1056 AA.
AC M7B540;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE SubName: Full=Syntaxin-binding protein 4 {ECO:0000313|EMBL:EMP33046.1};
GN ORFNames=UY3_09828 {ECO:0000313|EMBL:EMP33046.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP33046.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB537463; EMP33046.1; -; Genomic_DNA.
DR AlphaFoldDB; M7B540; -.
DR STRING; 8469.M7B540; -.
DR eggNOG; KOG3528; Eukaryota.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd00992; PDZ_signaling; 2.
DR CDD; cd00201; WW; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 2.30.42.10; -; 2.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR002014; VHS_dom.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR13856:SF28; TOM1-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR13856; VHS DOMAIN CONTAINING PROTEIN FAMILY; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF00790; VHS; 1.
DR Pfam; PF00397; WW; 1.
DR SMART; SM00228; PDZ; 2.
DR SMART; SM00288; VHS; 1.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50106; PDZ; 2.
DR PROSITE; PS50179; VHS; 1.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000031443};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 22..154
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 201..289
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT DOMAIN 399..442
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 450..524
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 999..1032
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT REGION 155..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 928..956
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 685..782
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 155..170
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..185
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 941..956
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1056 AA; 117676 MW; 800E872EDF097AAB CRC64;
MAFGKSQKDP FSTAVGHLIE RATIGVLPAE EWGQFMHICD IINTTDEGPK DAVKALKKRI
SKNCNHKEIR FTLSLLDMCM KNCGPSFQSL VVKKDFCKDK LVKLLQPRYN LPADTQDIIL
AFIRTWAYGF QGTVDVSEVK EVYLELLKKG VQFPSSDANP GTQKQRASSW PSEKPPPPSA
ASVKSIPVPR PPALTITLTP EQIGKLYSEL DMAKMNAKVM SAILTENVPG SENLDDMELL
QKLYKICRVM QERIVELLVA VQNEDVIAEL TRVNEDLNNV LLGHERFSRN RVRFLENQRL
QCEQAEIYSK QPSAPSCDLL VVNSSSSIPV SALVGTGPET PQFSELNESK SSLQAPHYYE
VMEFDPLARD YSTETIMGPY GINRAVHRIT FSDCQNGLGR LLTGDLILDV NGENLVGVTS
ERAVDVLRMA SATNHVSLLI TRDEEANDSA FQIITVSKGT GLGLNIVGGI NRNEGPLVYI
QEVIPGGDCH KDGRLKPGDQ LVSINKESMI GVSYEEAKSI INRTKLRSES AWEIAFIRQR
IFPGCFENPQ SPGSLLASSA GCGQQQTLLA FNLLSPPNEN PGSKVSTSYT MKTGFKKREQ
SPIPSADSSP ADVSVAAVAS NWTEDYGPQE RKISLNPTVR LKAEKLEMLD EAGRGPRPII
FGASEIASLL DSQLVSCDSL EMDDVERLKR ERNEALKEIS KLKEELSESV GLRKLLTEEL
QTVKQEAKAA VEEARALRSR IHLAEAAQRQ ARGMEMDYEE IIRLLEAEIT ELKAQLTDHS
GQNKDSVQDL RKRITVLDCQ LRKSESARKT FEVATAKLLQ FVEVVHEVLA DNSIPLSNLS
DRRGTLSTKT LLARLGRNGR TVTATLAAEA KELTKSVRAI LEVDLGKSET LRTVTQTYMM
RMYDSSEAKQ IKKAGCTKYL SAEIVSGRKG TQENAPTAHR TPVWRHHHHR RESRRRNISR
RYNPAAAFRI QMLYRSNRPK DTREILFGLS SYCAIPSEKG LPYGWEEAYT ADGIKYFINH
VTQTTSWIHP VTSALNLSCS EENEEDRTRE LPDPKS
//
