ID M7B7Q6_CHEMY Unreviewed; 1293 AA.
AC M7B7Q6;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Nephrocystin-3 {ECO:0000313|EMBL:EMP31575.1};
GN ORFNames=UY3_11286 {ECO:0000313|EMBL:EMP31575.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP31575.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
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DR EMBL; KB544907; EMP31575.1; -; Genomic_DNA.
DR STRING; 8469.M7B7Q6; -.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR GO; GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45641:SF1; NEPHROCYSTIN-3; 1.
DR PANTHER; PTHR45641; TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870); 1.
DR Pfam; PF13374; TPR_10; 1.
DR Pfam; PF13424; TPR_12; 3.
DR SMART; SM00028; TPR; 7.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 5.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000031443};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 899..932
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1098..1131
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1140..1173
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1182..1215
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1224..1257
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1034..1066
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 103..190
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1034..1050
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1293 AA; 146678 MW; 162848759CA16E2D CRC64;
MGTASSLVSP AGTGGEVIED TYGGGGGEAC EIPVEVKPKA RLLRSSFRRV GASRPGGLIG
ASFKSTASVQ ELECMAEYER LKKEYEIFRV SKNNEVASMV KKEAKLDLEN KRLRAELQAL
QKTYQKILRE KESALEAKYQ AMERAATFEH DRDKVKRQFK IFRETKENEI QDLLRAKREL
ETKLQRLQAQ GIQVFDPEES DSDDNCTEVT ATGAQSEYWT GGVLGSEPSM GSMMQLQQSF
RGPEFAHSSI DVEGPFANIN RDDWDAAIAS LLQVTPLFSH SLWSNTVRCY LINTDETQPE
VDIFIRNYSP KLQRICETLG YFFQVVHFPV ENGNHFQAVR KWEIEKSSLV ILFIHLTLPS
CLLEDCEEAL LKNPEGKPRL IYRRIEDGKV SSDPVQQLTE QVCYVNKAKL IDHMGGVEEG
AYETYNCVEK IIKQDILGCE STEVEGKDLG NKEESTAPEE EVFGDVLWDA HDEQEQMEAF
QQASNSTCEL GFEKLMQHSW LVSPLTLDPA KLLEEFPRWL EKLTARHQGS IIIIIDSIDQ
IQQAEKHMKW LIDPLPVNVR VIVSVNVETC PQAWRLWPTL HLEPLNSKDV KCLISAECSC
ADVKLTNEQE KKLEKHCRSA TTCNALYVTL LGKMIACARS AGNIDEILQQ CFQCQDTVSL
YRLVLRSVQE SMLNDKDKHL MREVLCLISV SHNGVSESEL MELYPELSCA MLASLVHSLH
KMCMLTYGCG LLKFQHLQAW ETVQLEYMEE GQKIISTYRE KLIDYFTVQL SQGRVTWRSA
DELPWLFQQQ GNKQKLHKCL LNLFVSQNLY KRGHFAELLS YWQLVGKDKS SMAAEYFDSL
KQYEKSCEGE ENMICLADLY ETLGRFLKDL GLLSQAVAPL QRSLEIRETA LDPDHPRVAQ
SLHQLAGVYV QWKKFGNAEQ LYKQALEISE NAYGAEHPRV ARELDALATL YQKQNKYEQA
EQLRKKSFKM RQKAARRKGN LFGFALLRQR ALQLEELTLG KDTPDNARTL NELGVLYYLQ
NNLEDRFIAS HLDTINRSPN TTGSASGTPA RERRKQSRQG SSSGRLATIP TATTAELFLK
RSLEMRERVL GPDHSDCAQS LNNLAALYNE KKHYDKAEEL YERALEIRRR ALAPDHPSLA
YTVKHLAVLY KKVGKLDKAV PLYELAVEIR QKSFGPKHPS VATALVNLAV LYCQMKKHIE
ALPLYECALK IYEDSFGHMH PRVGETLKNL AVLSYEGGDF EKAAELYKRA MEIKEAETSL
VGGKAASRPS SSGDTFSLRS TLSPNVFLDH GQR
//
