ID M7BFH2_CHEMY Unreviewed; 3369 AA.
AC M7BFH2;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=ATP-binding cassette sub-family A member 13 {ECO:0000313|EMBL:EMP34340.1};
GN ORFNames=UY3_08509 {ECO:0000313|EMBL:EMP34340.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP34340.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KB532689; EMP34340.1; -; Genomic_DNA.
DR STRING; 8469.M7BFH2; -.
DR eggNOG; KOG0059; Eukaryota.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF113; ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 13; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:EMP34340.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000031443};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1903..1923
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1949..1971
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1983..2007
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2014..2034
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2040..2064
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2085..2109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2562..2582
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2764..2784
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2814..2835
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2842..2862
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2874..2901
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2913..2931
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2959..2981
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2173..2406
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 3024..3262
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 3369 AA; 381075 MW; B15623102E7BFAA0 CRC64;
MATLVKNTEN EDLEFLIDQL KQIRKSLHHF FKKIKTVYIE NSVLDKLTGW LDSFENNSCS
WNLTNLWQMT QLFKETELDD ILQVLYLLPD AISLIQRLDH KNITDTLIEV YTFTSTQEAN
MSICTKEDLS NKIDRLLELL EVVADMPQES ARALSCLTAV ICWNLTTETP QNDPALRTCN
LNEHRNFLSI YNTIADVLEQ FKLTTPGGHA LCSNGDYRRE ITYKATCFFH QLKEWNSILL
KLSEIHNINS LALKQLLGFW NKLSVYVMAF GNSSTIAVYC SSTPKRQAAL QLIEALNNMT
STEMAMAKAI FEQLADLYHA LNLDRSTGMS IPKTLLTHLK SMANEISGAL NNEDVLSYFL
SAAQPLLTLS PVGNQTYMVL RALSALNRNN SLFGDFEALW LDRERGIQDL LVNFSVPNLL
SVIDKEVQLL SAAARKTCSL ALASLLKQFN SSSLETLLRS FEDFQEVARD WLYEYTNKNF
SRIINALVVL LANEKSSDDI VLIIKGITEF LELFRNGSKE DHIDISFVTD LLSGEKLNNV
HVAHTILQNS LLNMISDLTT EEEVLNLNDT DLQIMDFIDL FFDDAQYENY GKQIASFQNR
TMEMIREFLQ IIFPSSGGHY SNKMFVLLKN LHKDIIAEMR IFPKDDIGTP LNLDQYVNLK
EEVDGLKENM YDLIKNAAIS ENGTFHFESA KGLKFMRDLF NVLFKDFSVK NGSRSNYELF
TFVNHVLFNT SNPGDFAQLI RDLSRTLQFM RQTSAEMGNL MNFFNNHFKD FLVSYPTFRE
MVLTNLTELL ASVDKVFPLK NKQIIETTET LLDLISWSGG ANYTRNPFPE LAVDLGSLLW
ESNEFVKLAK IVEAIVKFLT LSKKASEKVA SCLELSINSN ATENLDYIEM VYSDLQRAVH
DAIEELTETE TAELLLSNHH QVADLGKAFL DLTYLSIRDK LSRSYGSGTA NISTRLVANL
SKLSGLNDIA GEIAEFLANG QNYSAELERL VAIVTRASIN SSDDTASLIE DLLDFFVPIN
DIISKIHLAS RLNFTHDPIN EEQWEGIQEM ITYLGKGNIT AIKASIRAVA DLFLGAFWKN
HLSEHDLNLL LTYADNEDDF LKVLEVTMES FKLMKNVSEG SFNLWSLFAS LMNQNITYQQ
KEPYIWETIT EDSLNRTNPW IELLHLSADQ QVNSTRALLQ TVMAFFANGT SDVADVAQLE
NSILRMMHDF DLIFKPLSSY EKYARQLVNL AEYWRQGPLK EQRVSEMCQG FQKHLSPANA
QLLQKVQIMA LSVFTILSDN PTVISNLLCA FTSCKDGLTR CFLLSAIEGI NLVHEQYQDI
ETMLSASNEG ECGNHLYVNR NLSSTLESFQ RALQNTTYSS CECQLTFENI QKHMQTLAGN
LEAPLSGNRV VAFVSNFSLP NDVKIKDCVH NVPELARDLR SLVNISEETI NTFLEANFSQ
SKLLYSALAV ALAGRCDEEI LSLLLTLPAN GKISLAVKEL CSLPALDLYT MITVIAQNLN
LRYIIYKIMI PSEVNKLLSA MLEVVTSISS LSNKGQHVLE NLPMFLQAFK SIDLLDISAF
QQFLQGGKSR SSIVGSLQSL IRAVCKEESS FFSNTNMFID MPRITELLED DMAKYSIPED
STPFCLQLYQ EILQSPNGAL VWTFLKPLLH GKILYTPNSK TFNMVIEKAN HTFGFVDNLK
IYSEAWLRMS EVFKSSENFL MVNQLQEALQ NSFIKNFIES HLNIDVGNLI GKLQEYESMM
EKMLHNSVTE QINLLAQLMV NISSCVLLDR FQHFESVEKL EAKAQELMQQ NNFLASIIFN
TSSNRRRRQD SASHLSQHIS YTIRTSILYS MRTDLIKNPV WKSHPPNLPG DGFRYNYIFV
PLQDMIEKAI IAVHAGADAS EAEIQVQAMP YPCHISDLFL NNIGFFFPFI MMLAWMVSVA
GMVRKRVYER EIHLEEYMKT MGVNPAIHFL AWFLENVIVL TISSCALVII LKVSGIIVYS
DGFLVFLFLL DFGVAVVMLS YLLGAFFSSA NTAALCASLI YVISFLPYIV LLVLENQLSF
ALQIITCFLS TTAFGQGVFF ITFFESQEIG IQWSNMYQPL AQGGSMTFGW ASWMIFFDSI
LYLLVGWYFS NVIPGRLGFR KPWYFPFNIS YWKELCGTEK RRKHLNSNLV FVNEGSLPPD
ERRMSEGGSP VGVILMSLTK KYTDNKKTAV KDLNLIFYKG QITALLGANG AGKTTIISML
TGLYPPSSGT IIINGRDIHT ELAAIRMEMG VCPQYDVLFD TLTVREHLLF YGSVKAPLWT
KKQLHQQVSR ALEDVDLSHH QFKHVGALSG GMKRRLSIAI SFIGNSKTVV LDEPTSGVDP
CSRRRIWDIL LKYRAGCTLI FTTHHLDEAE VLSDRIAILQ QGQLRCCGPP SYLKETYGQG
YRLTLIKKPS AFEIEDPEYI SQVTSLVQFY VPEAFLKENS GSELTYVIPM KADKAFFNGL
FQAMDENLER LHVTGYGISD TTLEEVFLKL LQYTEQKPQV PLAEELGLPH INSPESTYQN
CSSLLDARSV RGTRLVLTQI AALLMKRFHH TRRDWRGALS NVLLPVLFVA MAMALFTVKP
LAIDYPSLKL MPGLYDNAES SFFRKNDSCW QTEPSPPQEF LDACGCVTDH RKCPSFNVSA
AYLENRKGHV LYNLSGFSVE EYLIMSTNKA RYGGWSFGVK TSPELQDQKL NKTYSKPLAK
VWYSQKGFHS LPSYLNQLNN LILWMNLPPS VDWRQYGITL YSHPYGGALL DEDKIMENVR
QCGVALCIML GFSILMASIG NSVVKDRVSG TKRLQHISGL GYKTYWLANF LYDMLFYLVP
VGLCISVIAA FQLSAFTFRE NLAATALLLI LFGYATLPWM YLMSRFFSSS DIAFISYISL
NFVFGLCTML LTLLPHLLAT ISKAQSLQNI YNILKWAFIV FPPFCLGQGL LELSYNQIKF
DLTSSFGIDS YVSPFEMNFL GWIFVEMALQ GTVILLLRIL LHWDLLQKLR SHCSIGSTVS
PSEDEDVQVE RKRLFGGRTQ NDILLLYNLR KCYQGFSKRN TAVKDISLGI PRGECFGLLG
TNGAGKSTTF KMLTGDITPS GGRAVMRTPT GSEMDILSAS SEGILIGYCP QQDALDELLT
GWEHLYYYCS LRGVPKQCIH KVAGDLVSRL HLDTHINKLV RTYSGGTKRK LSTALALIGK
PQILLLDEPS SGMDPCSKRY LWKAIMKEVQ DGCAAVLTSH SMEECEALCT RLAIMVDGSF
RCLGSPQHIK NRFGDGYSVK VWLNKETSNH GAILDYLQLH FPGTQFKTIR SDKQEQHLNL
QEYRVPYGCG RLPELFKVLE NHKVLLQIKH YSINETTLEQ VFINFATQQQ ETSYCAQESS
TNHHHHLPV
//
