ID M7BJM3_CHEMY Unreviewed; 690 AA.
AC M7BJM3;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=mRNA export factor GLE1 {ECO:0000256|ARBA:ARBA00026227};
DE AltName: Full=GLE1 RNA export mediator {ECO:0000256|ARBA:ARBA00030897};
DE AltName: Full=GLE1-like protein {ECO:0000256|ARBA:ARBA00031503};
DE AltName: Full=Nucleoporin GLE1 {ECO:0000256|ARBA:ARBA00029983};
GN ORFNames=UY3_04704 {ECO:0000313|EMBL:EMP38126.1};
OS Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP38126.1, ECO:0000313|Proteomes:UP000031443};
RN [1] {ECO:0000313|Proteomes:UP000031443}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23624526; DOI=10.1038/ng.2615;
RA Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT into the development and evolution of the turtle-specific body plan.";
RL Nat. Genet. 45:701-706(2013).
CC -!- FUNCTION: Required for the export of mRNAs containing poly(A) tails
CC from the nucleus into the cytoplasm. May be involved in the terminal
CC step of the mRNA transport through the nuclear pore complex (NPC).
CC {ECO:0000256|ARBA:ARBA00024680}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nuclear pore complex
CC {ECO:0000256|ARBA:ARBA00004567}.
CC -!- SIMILARITY: Belongs to the GLE1 family.
CC {ECO:0000256|ARBA:ARBA00011056}.
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DR EMBL; KB520693; EMP38126.1; -; Genomic_DNA.
DR AlphaFoldDB; M7BJM3; -.
DR STRING; 8469.M7BJM3; -.
DR eggNOG; KOG2412; Eukaryota.
DR Proteomes; UP000031443; Unassembled WGS sequence.
DR GO; GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
DR GO; GO:0016973; P:poly(A)+ mRNA export from nucleus; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.510; GLE1-like; 1.
DR InterPro; IPR012476; GLE1.
DR InterPro; IPR038506; GLE1-like_sf.
DR PANTHER; PTHR12960; GLE-1-RELATED; 1.
DR PANTHER; PTHR12960:SF0; MRNA EXPORT FACTOR GLE1; 1.
DR Pfam; PF07817; GLE1; 1.
PE 3: Inferred from homology;
KW mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW Nuclear pore complex {ECO:0000256|ARBA:ARBA00023132};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000031443};
KW Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT REGION 62..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 197..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 341..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..110
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 341..362
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 690 AA; 79330 MW; A09783159D33B279 CRC64;
MPSERYRWET LEALKGSSKG QLSYSQDWLL RGEDILEGCR SPPKLSSYSG WVLDRVISQS
LQETPLSRSS TPNESIPHTD DQPPSLAKTT SPASELGSSP LSSAAPSESK GNEDLSLLET
DHKVHLLVLP SKVTEVEGCI WMYKEVHRLK GKEGLRQRQE QQEQMVRAVS DMASEQLKRF
DELKELKQHQ EYQDLQEVME KSSREAQGQQ EKLKEEHRHR AKILNLKLRE AEQERQRQEE
LERLRKEEGQ ERLRRLYSIQ EEVLQLNQQI DPNYRHKDLP RIDLSGFSNR GNQICGLVSG
LIRTTSERGF PTQVDVANTE RALQEMRGLI SSMQQEIATA LEEKRKRDEE EERERQKELQ
KQEQLKAQTP VPAQHPRGKE QKEVLGLQVK AEESTMQWYQ QLQDASDQCV ASFSGLTDCK
DNQVKNIRMD LQKAASIPVS QISSIAGSQL REIFDKINNL LSGKSVQSGG RTVSVTQHPQ
GLDFVYYKLA EKFVKQGEEE VASHHEAAFP IAVVASGIWE LHPRVGDLIL AHLHKKCPYS
VPFYPAFKEG TSIEEYQRIL GYQVKDSKVE QQDNFLKRMS GMIRLYAAII QLRWPYGNKQ
VTHPHGLGHG WRWLAQMLNM EPLSDVTATL LFDFLEVCGN ALMKHYQVQF WKMLLLIRED
YFHRIEAITI SGQMGSLMRL KQFLEVKHSL
//
