ID   M7BPJ2_CHEMY            Unreviewed;       954 AA.
AC   M7BPJ2;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   24-JAN-2024, entry version 36.
DE   SubName: Full=Run domain Beclin-1 interacting and cystein-rich containing protein {ECO:0000313|EMBL:EMP37635.1};
GN   ORFNames=UY3_05149 {ECO:0000313|EMBL:EMP37635.1};
OS   Chelonia mydas (Green sea-turtle) (Chelonia agassizi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira;
OC   Americhelydia; Chelonioidea; Cheloniidae; Chelonia.
OX   NCBI_TaxID=8469 {ECO:0000313|EMBL:EMP37635.1, ECO:0000313|Proteomes:UP000031443};
RN   [1] {ECO:0000313|Proteomes:UP000031443}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23624526; DOI=10.1038/ng.2615;
RA   Wang Z., Pascual-Anaya J., Zadissa A., Li W., Niimura Y., Huang Z., Li C.,
RA   White S., Xiong Z., Fang D., Wang B., Ming Y., Chen Y., Zheng Y.,
RA   Kuraku S., Pignatelli M., Herrero J., Beal K., Nozawa M., Li Q., Wang J.,
RA   Zhang H., Yu L., Shigenobu S., Wang J., Liu J., Flicek P., Searle S.,
RA   Wang J., Kuratani S., Yin Y., Aken B., Zhang G., Irie N.;
RT   "The draft genomes of soft-shell turtle and green sea turtle yield insights
RT   into the development and evolution of the turtle-specific body plan.";
RL   Nat. Genet. 45:701-706(2013).
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DR   EMBL; KB521472; EMP37635.1; -; Genomic_DNA.
DR   AlphaFoldDB; M7BPJ2; -.
DR   STRING; 8469.M7BPJ2; -.
DR   eggNOG; KOG1829; Eukaryota.
DR   eggNOG; KOG4381; Eukaryota.
DR   Proteomes; UP000031443; Unassembled WGS sequence.
DR   GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   CDD; cd17686; RUN_RUBCN; 1.
DR   Gene3D; 1.20.58.900; -; 1.
DR   InterPro; IPR025258; RH_dom.
DR   InterPro; IPR048569; RUBC_PIKBD.
DR   InterPro; IPR004012; Run_dom.
DR   InterPro; IPR037213; Run_dom_sf.
DR   PANTHER; PTHR45971; PHOX (PX) DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45971:SF3; RUN DOMAIN BECLIN-1-INTERACTING AND CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13901; RH_dom; 1.
DR   Pfam; PF21054; RUBC_PIKBD; 2.
DR   Pfam; PF02759; RUN; 1.
DR   SMART; SM01175; DUF4206; 1.
DR   SMART; SM00593; RUN; 1.
DR   SUPFAM; SSF140741; RUN domain-like; 1.
DR   PROSITE; PS50826; RUN; 1.
PE   4: Predicted;
KW   Autophagy {ECO:0000256|ARBA:ARBA00023006};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Endosome {ECO:0000256|ARBA:ARBA00022753};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000031443}.
FT   DOMAIN          47..188
FT                   /note="RUN"
FT                   /evidence="ECO:0000259|PROSITE:PS50826"
FT   REGION          224..408
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          475..506
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        242..277
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        293..367
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        374..408
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   954 AA;  107742 MW;  740A6520C6F8699C CRC64;
     MLWLCQEQSG LKKSDQSCLH GKEHWKLLGN LKTTVEGLVS SNNPNVWSKY GGLERLCRDM
     HSILYHGLIH DKVYCRQTDY WQFVKDIRWL SPHSAHHVEK FISLHEHGQP NADGVSRRAV
     AELWLQHSLQ FHCLSAQLKP LLENRQYIRK FYTDAAFLLS DAHVTAMLQC LEAVEQNNPR
     LLAQIDTSMV RRAPALYRRP ASSSVCSSTS QPLENAPYNV SLLLPEDRSP LGQPGLPRLS
     VTSPRDDSSS VSEMSTSTVT SQSEDPWAGS QDDAQSDAND GPEYLAIGNL GRQGRACSSQ
     SSTSSSITNS NKSSSSNLFS SSSSQKPESI SSVEDQGASS GSRGMSLLRR SSFSEGQTST
     PQGILKRSHA RSHSDTNVAS GKTPESQGDT SRVMGHVSGS TQSSEVSTPS SLYMEYDAGQ
     YLSSGEGMFR RPSEGQSLIS YLSEQDFGSC ADLEKENAHF SISESLIAAI ELMKCNVMNR
     RLEEEEEESD KEIQELKQKI RIRRQQIRTK HVLPAYREVG SDSFVATDSE SQFSSRDSMW
     LSDSGSAEDV EEYEIRDADI RRDAASSRKS FLSSESISHS FLHSNSAEAV AMGLLKQFEG
     MQLPAASELD WLVPEQDAPQ KGPRRSLKKL FKRCQWYKKR QLSKKLRRLL PIPDSLPISP
     DDGEHADIYK LRIRVRGNLE WAPPRPQIIF NIHPAPTRKV AVAKQNYRCA GCGIRTDPDY
     IKRLRYCEYL GKYFCQCCHE NTQMVIPSRI LRKWDFSKYC VSNFSRDLLS KIWSDPLFSV
     QDLNAALYRK VKALNQVRLL RIQLFHLKNM FKTCRLAKEL LDSFDLVPGH LTEDLHLYSL
     NDLNATKKGE LVPRLTELIK AGTLHVERCM LCQAKGFICE FCQEDDIIFP FELNKCRTCE
     ECKACYHKSC FKSGCCPRCE RLHARRELLA KQSMESYISD YEEEEQPPEA VAAT
//