ID M7MYQ0_9MICC Unreviewed; 442 AA.
AC M7MYQ0;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 28-MAR-2018, entry version 37.
DE RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01020005};
GN Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN ORFNames=ADIAG_00083 {ECO:0000313|EMBL:EMR00076.1};
OS Paeniglutamicibacter gangotriensis Lz1y.
OC Bacteria; Actinobacteria; Micrococcales; Micrococcaceae;
OC Paeniglutamicibacter.
OX NCBI_TaxID=1276920 {ECO:0000313|EMBL:EMR00076.1, ECO:0000313|Proteomes:UP000012015};
RN [1] {ECO:0000313|EMBL:EMR00076.1, ECO:0000313|Proteomes:UP000012015}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lz1y {ECO:0000313|EMBL:EMR00076.1,
RC ECO:0000313|Proteomes:UP000012015};
RX PubMed=23766407;
RA Shivaji S., Ara S., Bandi S., Singh A., Kumar Pinnaka A.;
RT "Draft Genome Sequence of Arthrobacter gangotriensis Strain Lz1yT,
RT Isolated from a Penguin Rookery Soil Sample Collected in Antarctica,
RT near the Indian Station Dakshin Gangotri.";
RL Genome Announc. 1:e00347-13(2013).
CC -!- FUNCTION: Plays an important role in the initiation and regulation
CC of chromosomal replication. Binds to the origin of replication; it
CC binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC ECO:0000256|RuleBase:RU000577}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC ECO:0000256|SAAS:SAAS00747961}.
CC -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC ECO:0000256|SAAS:SAAS00555179}.
CC -!- CAUTION: The sequence shown here is derived from an
CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC preliminary data. {ECO:0000313|EMBL:EMR00076.1}.
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DR EMBL; AOCK01000001; EMR00076.1; -; Genomic_DNA.
DR EnsemblBacteria; EMR00076; EMR00076; ADIAG_00083.
DR PATRIC; fig|1276920.7.peg.79; -.
DR OrthoDB; POG091H02FF; -.
DR Proteomes; UP000012015; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR CDD; cd06571; Bac_DnaA_C; 1.
DR Gene3D; 1.10.1750.10; -; 1.
DR HAMAP; MF_00377; DnaA_bact; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR001957; Chromosome_initiator_DnaA.
DR InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR InterPro; IPR013317; DnaA.
DR InterPro; IPR013159; DnaA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010921; Trp_repressor/repl_initiator.
DR PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR Pfam; PF00308; Bac_DnaA; 1.
DR Pfam; PF08299; Bac_DnaA_C; 1.
DR PRINTS; PR00051; DNAA.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00760; Bac_DnaA_C; 1.
DR SUPFAM; SSF48295; SSF48295; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR TIGRFAMs; TIGR00362; DnaA; 1.
DR PROSITE; PS01008; DNAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Complete proteome {ECO:0000313|Proteomes:UP000012015};
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW ECO:0000256|SAAS:SAAS00747973};
KW DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00748008};
KW Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW Reference proteome {ECO:0000313|Proteomes:UP000012015}.
FT DOMAIN 133 261 AAA. {ECO:0000259|SMART:SM00382}.
FT DOMAIN 345 414 Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT NP_BIND 141 148 ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
FT COILED 414 434 {ECO:0000256|SAM:Coils}.
SQ SEQUENCE 442 AA; 49646 MW; 2812AD7F5E819D21 CRC64;
MQRAFAALAQ PQGLIGTTLL LAVPNELTRD VLQTQLKDPL EQSLKLVFQS DIRCAFSIDS
DLVPEEAPAP PVELPPVPKA RISEPLPQPS PPSNSQEFGR LNPKYIFDTF VIGSSNRFAH
AAAVAVAEAP AKAYNPLFIY GDSGLGKTHL LHAIGHYARH LYNGIRVRYV NSEEFTNDFI
NSIRDDEGAS FKQTYRNVDI LLIDDIQFLA NKDATQEEFF HTFNALHNHN KQVVITSDLP
PKQLSGFEDR MRSRFEWGLL TDIQPPELET RIAILRKKAN AENLSAPDEV MEYIASKIST
NIRELEGALI RVTAFASLNN QTVDMSLAET VLKDLITDEG AQEITPATIV AQTAEYFNLT
IEELTSKSRT RTLVTARQIA MYLLRELTDM SLPKIGQELG GRDHTTVIHA DRKIRELMAE
RRAIFNQVTE LTNRIKQRQR EG
//
