ID M7NXX8_9GAMM Unreviewed; 649 AA.
AC M7NXX8;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Succinate dehydrogenase flavoprotein subunit {ECO:0000313|EMBL:EMR12061.1};
DE EC=1.3.5.1 {ECO:0000313|EMBL:EMR12061.1};
GN Name=sdhA {ECO:0000313|EMBL:EMR12061.1};
GN ORFNames=MPL1_12371 {ECO:0000313|EMBL:EMR12061.1};
OS Methylophaga lonarensis MPL.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Methylophaga.
OX NCBI_TaxID=1286106 {ECO:0000313|EMBL:EMR12061.1, ECO:0000313|Proteomes:UP000012019};
RN [1] {ECO:0000313|EMBL:EMR12061.1, ECO:0000313|Proteomes:UP000012019}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MPL {ECO:0000313|EMBL:EMR12061.1,
RC ECO:0000313|Proteomes:UP000012019};
RX PubMed=23661481;
RA Shetty S.A., Marathe N.P., Munot H., Antony C.P., Dhotre D.P.,
RA Murrell J.C., Shouche Y.S.;
RT "Draft Genome Sequence of Methylophaga lonarensis MPLT, a Haloalkaliphilic
RT (Non-Methane-Utilizing) Methylotroph.";
RL Genome Announc. 1:E00202-13(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMR12061.1}.
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DR EMBL; APHR01000075; EMR12061.1; -; Genomic_DNA.
DR RefSeq; WP_009727417.1; NZ_APHR01000075.1.
DR AlphaFoldDB; M7NXX8; -.
DR STRING; 1286106.MPL1_12371; -.
DR PATRIC; fig|1286106.3.peg.2472; -.
DR eggNOG; COG1053; Bacteria.
DR OrthoDB; 9806724at2; -.
DR Proteomes; UP000012019; Unassembled WGS sequence.
DR GO; GO:0102040; F:fumarate reductase (menaquinone); IEA:UniProtKB-EC.
DR GO; GO:0008177; F:succinate dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR011280; Succ_DH/Fum_Rdt_flav_su.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR NCBIfam; TIGR01811; sdhA_Bsu; 1.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF53; SUCCINATE DEHYDROGENASE FLAVOPROTEIN SUBUNIT; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EMR12061.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000012019}.
FT DOMAIN 42..452
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 514..648
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT ACT_SITE 337
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR630664-50"
SQ SEQUENCE 649 AA; 71944 MW; 29B3ECAC2234B79C CRC64;
MMESLPFDFD AHCPKGPLDQ RWTQHKYHLQ VVSPANRKHY KVIVVGTGLA GASAAASLAE
MGYQVESFCF QDSPRRAHSI AAQGGINAAK NYHNDGDSVW RLFYDMIKGG DFRARESNVF
RLAELSTSII DQAVAQGVPF AREYSGYLAN RSFGGAQVSR TFYARGQTGQ QLLLGAYQAM
SRQIAAGRIT QHSRCEMQDL IMLNGQAKGI VSRNLVTGEL QAHLADCVVL CTGGYGNAFY
LSTNAKGCNT SAIWRAHKHG ALFANPCFTQ IHPTCIPQHG ELQSKLTLMS ESLRNDGRIW
APKDIADCDK APATIAEQQR DYFLERLYPA FGNLVPRDIA SRAVKHICDA GRGVGVEIAG
QRRGVYLDFA DAIAQQGLDV INEKYGNLFD MYERITAEDP RQTPMRIYPA VHYTMGGLWV
DYNLMTTVDG LFAGGEANFS DHGANRLGAS ALMQGLADGY FILPATVSDY LAKQHPIRPQ
DFAAEARNAI ETVRLRLDRL MNAPSPETAP DVFHRELGEI LWHACGMARE ASQLKSAITE
IQQLRERFWQ HVKVTGSSDT LNQTLERAAR VADFLELGEL MCLDALQREE SCGCHARVEH
LTDGGEVQRD DMQFASVSAW QYSGDVSEPR LLQEPLLFEF VSPGVRSYR
//
