ID M7PKN3_PNEMU Unreviewed; 89 AA.
AC M7PKN3;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Transcription elongation factor 1 homolog {ECO:0000256|RuleBase:RU364033};
GN ORFNames=PNEG_03602 {ECO:0000313|EMBL:EMR11019.1};
OS Pneumocystis murina (strain B123) (Mouse pneumocystis pneumonia agent)
OS (Pneumocystis carinii f. sp. muris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Pneumocystomycetes; Pneumocystaceae; Pneumocystis.
OX NCBI_TaxID=1069680 {ECO:0000313|EMBL:EMR11019.1, ECO:0000313|Proteomes:UP000011958};
RN [1] {ECO:0000313|Proteomes:UP000011958}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B123 {ECO:0000313|Proteomes:UP000011958};
RX PubMed=26899007; DOI=10.1038/ncomms10740;
RA Ma L., Chen Z., Huang D.W., Kutty G., Ishihara M., Wang H., Abouelleil A.,
RA Bishop L., Davey E., Deng R., Deng X., Fan L., Fantoni G., Fitzgerald M.,
RA Gogineni E., Goldberg J.M., Handley G., Hu X., Huber C., Jiao X., Jones K.,
RA Levin J.Z., Liu Y., Macdonald P., Melnikov A., Raley C., Sassi M.,
RA Sherman B.T., Song X., Sykes S., Tran B., Walsh L., Xia Y., Yang J.,
RA Young S., Zeng Q., Zheng X., Stephens R., Nusbaum C., Birren B.W.,
RA Azadi P., Lempicki R.A., Cuomo C.A., Kovacs J.A.;
RT "Genome analysis of three Pneumocystis species reveals adaptation
RT mechanisms to life exclusively in mammalian hosts.";
RL Nat. Commun. 7:10740-10740(2016).
CC -!- FUNCTION: Transcription elongation factor implicated in the maintenance
CC of proper chromatin structure in actively transcribed regions.
CC {ECO:0000256|ARBA:ARBA00003357, ECO:0000256|RuleBase:RU364033}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU364033}.
CC -!- SIMILARITY: Belongs to the ELOF1 family.
CC {ECO:0000256|ARBA:ARBA00009730, ECO:0000256|RuleBase:RU364033}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMR11019.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AFWA02000002; EMR11019.1; -; Genomic_DNA.
DR RefSeq; XP_007872738.1; XM_007874547.1.
DR AlphaFoldDB; M7PKN3; -.
DR STRING; 1069680.M7PKN3; -.
DR GeneID; 19897289; -.
DR VEuPathDB; FungiDB:PNEG_03602; -.
DR eggNOG; KOG3214; Eukaryota.
DR HOGENOM; CLU_105983_0_3_1; -.
DR OrthoDB; 276470at2759; -.
DR Proteomes; UP000011958; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 2.20.25.190; -; 1.
DR InterPro; IPR007808; Elf1.
DR InterPro; IPR038567; T_Elf1_sf.
DR PANTHER; PTHR20934:SF0; TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG; 1.
DR PANTHER; PTHR20934; UNCHARACTERIZED; 1.
DR Pfam; PF05129; Elf1; 1.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU364033};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364033};
KW Reference proteome {ECO:0000313|Proteomes:UP000011958};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU364033};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU364033};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU364033};
KW Zinc-finger {ECO:0000256|RuleBase:RU364033}.
SQ SEQUENCE 89 AA; 10189 MW; C611BF7FEB8D0C5A CRC64;
MGKRKTKMKR PKPKPRAPLD KTFNCLFCNH EKSTLICKVC GQTHQSIIHN LSAPVDIYSD
WIDACDAVAN KTNRNLTQEL NLNNNDYNN
//
