ID M7PM04_PNEMU Unreviewed; 430 AA.
AC M7PM04;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
GN ORFNames=PNEG_00512 {ECO:0000313|EMBL:EMR11499.1};
OS Pneumocystis murina (strain B123) (Mouse pneumocystis pneumonia agent)
OS (Pneumocystis carinii f. sp. muris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Pneumocystomycetes; Pneumocystaceae; Pneumocystis.
OX NCBI_TaxID=1069680 {ECO:0000313|EMBL:EMR11499.1, ECO:0000313|Proteomes:UP000011958};
RN [1] {ECO:0000313|Proteomes:UP000011958}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B123 {ECO:0000313|Proteomes:UP000011958};
RX PubMed=26899007; DOI=10.1038/ncomms10740;
RA Ma L., Chen Z., Huang D.W., Kutty G., Ishihara M., Wang H., Abouelleil A.,
RA Bishop L., Davey E., Deng R., Deng X., Fan L., Fantoni G., Fitzgerald M.,
RA Gogineni E., Goldberg J.M., Handley G., Hu X., Huber C., Jiao X., Jones K.,
RA Levin J.Z., Liu Y., Macdonald P., Melnikov A., Raley C., Sassi M.,
RA Sherman B.T., Song X., Sykes S., Tran B., Walsh L., Xia Y., Yang J.,
RA Young S., Zeng Q., Zheng X., Stephens R., Nusbaum C., Birren B.W.,
RA Azadi P., Lempicki R.A., Cuomo C.A., Kovacs J.A.;
RT "Genome analysis of three Pneumocystis species reveals adaptation
RT mechanisms to life exclusively in mammalian hosts.";
RL Nat. Commun. 7:10740-10740(2016).
CC -!- SIMILARITY: Belongs to the AAA ATPase family. PCH2 subfamily.
CC {ECO:0000256|ARBA:ARBA00007271}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMR11499.1}.
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DR EMBL; AFWA02000001; EMR11499.1; -; Genomic_DNA.
DR RefSeq; XP_007872400.1; XM_007874209.1.
DR AlphaFoldDB; M7PM04; -.
DR STRING; 1069680.M7PM04; -.
DR GeneID; 19894210; -.
DR VEuPathDB; FungiDB:PNEG_00512; -.
DR eggNOG; KOG0744; Eukaryota.
DR HOGENOM; CLU_028208_0_1_1; -.
DR OMA; WEGLWES; -.
DR OrthoDB; 275461at2759; -.
DR Proteomes; UP000011958; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR CDD; cd19508; RecA-like_Pch2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR044539; Pch2-like.
DR PANTHER; PTHR45991; PACHYTENE CHECKPOINT PROTEIN 2; 1.
DR PANTHER; PTHR45991:SF1; PACHYTENE CHECKPOINT PROTEIN 2 HOMOLOG; 1.
DR Pfam; PF00004; AAA; 1.
DR PRINTS; PR00830; ENDOLAPTASE.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003651};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003651};
KW Reference proteome {ECO:0000313|Proteomes:UP000011958}.
FT DOMAIN 174..326
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 430 AA; 48932 MW; A8C0E89BEF9BB01F CRC64;
MEKSEINKDE EEFKKPIIHK PLLHIECSLK EKSTCRFDMA SHYVRRFLLE NFSSLTLNTE
FRNFEDEPLL MKHIEQIRVV EVSGSNKEIL YLDEVDLDVH IYQLNNSLPF TNNFDDQDLE
DGPMAIVTEL PSLSLEGLWD NLIFEDNIKN NLLHFIHTVM LFSDKDVNFN IVTWNRLILL
HGPPGTGKTS LCRALAQKLS IRLSNKFSRG RIVEVNSHSL FSKWFSESGK LVGKMFQQIH
EMVEDEDSFV CVLIDEVESL TAARKAAASG LEPSDGLRVV NSLLTQLDKL KPHKNVFILT
TSNLLEAMDP AFVDRIDIKQ YVGDPNPDAI FAILQSCINE LGRKGLIGDG IPVPSFTEAS
ISLYSQPNSY SSRLYRIAVD CKGLSGRTLR RLPVLAHAKY LQRPCCTMDE MLCSLEKVVK
EELEFSMKIC
//
