ID   M7PUF5_9GAMM            Unreviewed;       506 AA.
AC   M7PUF5;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   SubName: Full=NAD-dependent epimerase/dehydratase {ECO:0000313|EMBL:EMR14099.1};
GN   ORFNames=MPL1_01588 {ECO:0000313|EMBL:EMR14099.1};
OS   Methylophaga lonarensis MPL.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC   Piscirickettsiaceae; Methylophaga.
OX   NCBI_TaxID=1286106 {ECO:0000313|EMBL:EMR14099.1, ECO:0000313|Proteomes:UP000012019};
RN   [1] {ECO:0000313|EMBL:EMR14099.1, ECO:0000313|Proteomes:UP000012019}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MPL {ECO:0000313|EMBL:EMR14099.1,
RC   ECO:0000313|Proteomes:UP000012019};
RX   PubMed=23661481;
RA   Shetty S.A., Marathe N.P., Munot H., Antony C.P., Dhotre D.P.,
RA   Murrell J.C., Shouche Y.S.;
RT   "Draft Genome Sequence of Methylophaga lonarensis MPLT, a Haloalkaliphilic
RT   (Non-Methane-Utilizing) Methylotroph.";
RL   Genome Announc. 1:E00202-13(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMR14099.1}.
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DR   EMBL; APHR01000007; EMR14099.1; -; Genomic_DNA.
DR   AlphaFoldDB; M7PUF5; -.
DR   STRING; 1286106.MPL1_01588; -.
DR   PATRIC; fig|1286106.3.peg.323; -.
DR   eggNOG; COG0451; Bacteria.
DR   Proteomes; UP000012019; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 3.
DR   Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43574; EPIMERASE-RELATED; 1.
DR   PANTHER; PTHR43574:SF86; UDP-GLUCOSE 4-EPIMERASE_UDP-SULFOQUINOVOSE SYNTHASE; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000012019}.
FT   DOMAIN          14..314
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
FT   REGION          68..107
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        82..107
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   506 AA;  55356 MW;  05417094094CA6BD CRC64;
     MQTNDTTALK NKRILVTGSA GFIGFHLTKA LLSEGANVIG IDNLNDYYEP ALKQARLDEL
     DKFHASISAP AKSRDSDDAS DAATQNSETV VNKNSAVSAP TSDLSAPTSV IPVPTSVIPA
     QAGIQSVSKT SPEYQFIKMD LADRAAIESL FKTHHFDIVV NLAAQAGVRY SLENPHAYVD
     SNLIGFVNIL EGCRHAKVGH LVYASSSSVY GMNIKQPFST EDRVDYPISL YAATKKANEL
     MAHTYSHLYG IPTTGLRFFT VYGPWGRPDM AYYKFTKAIL EDKPIDIYNH GQMKRDFTYI
     DDIVDGILRV MVKPPQLESD TSSTTTATSA PNIVIPAPTP DTLAPNSVIP APNSVIPAQA
     GIHDDKNNRH CEERSDAAIQ SNQENRHCEE RSDVAIQSNH SGNKITNAQA PYKIYNIGNN
     QPVTLRHFIT AIENACGKKA IENSLPMQAG DVPITYADID DLMADTGFKP TTSIDSGIAR
     FAEWYKLFYT DNQSQNKTSL NSDITE
//