ID M7SQL8_EUTLA Unreviewed; 723 AA.
AC M7SQL8;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=beta-glucosidase {ECO:0000256|ARBA:ARBA00012744};
DE EC=3.2.1.21 {ECO:0000256|ARBA:ARBA00012744};
GN ORFNames=UCREL1_4237 {ECO:0000313|EMBL:EMR68754.1};
OS Eutypa lata (strain UCR-EL1) (Grapevine dieback disease fungus) (Eutypa
OS armeniacae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Diatrypaceae; Eutypa.
OX NCBI_TaxID=1287681 {ECO:0000313|EMBL:EMR68754.1, ECO:0000313|Proteomes:UP000012174};
RN [1] {ECO:0000313|Proteomes:UP000012174}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCR-EL1 {ECO:0000313|Proteomes:UP000012174};
RX PubMed=23723393; DOI=10.1128/genomeA.00228-13;
RA Blanco-Ulate B., Rolshausen P.E., Cantu D.;
RT "Draft genome sequence of the grapevine dieback fungus Eutypa lata UCR-
RT EL1.";
RL Genome Announc. 1:E0022813-E0022813(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-glucosyl residues
CC with release of beta-D-glucose.; EC=3.2.1.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000448};
CC -!- PATHWAY: Glycan metabolism; cellulose degradation.
CC {ECO:0000256|ARBA:ARBA00004987}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336}.
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DR EMBL; KB706189; EMR68754.1; -; Genomic_DNA.
DR RefSeq; XP_007792161.1; XM_007793970.1.
DR AlphaFoldDB; M7SQL8; -.
DR STRING; 1287681.M7SQL8; -.
DR KEGG; ela:UCREL1_4237; -.
DR eggNOG; ENOG502QR4D; Eukaryota.
DR HOGENOM; CLU_004542_2_3_1; -.
DR OMA; MTDWNAQ; -.
DR OrthoDB; 5486783at2759; -.
DR Proteomes; UP000012174; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR026891; Fn3-like.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR42715; BETA-GLUCOSIDASE; 1.
DR PANTHER; PTHR42715:SF29; BETA-GLUCOSIDASE L-RELATED; 1.
DR Pfam; PF14310; Fn3-like; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SMART; SM01217; Fn3_like; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EMR68754.1};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW Reference proteome {ECO:0000313|Proteomes:UP000012174};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..723
FT /note="beta-glucosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004084870"
FT DOMAIN 642..711
FT /note="Fibronectin type III-like"
FT /evidence="ECO:0000259|SMART:SM01217"
SQ SEQUENCE 723 AA; 76033 MW; D56572D5E90F6F10 CRC64;
MRSHFLTVLA AALPAALAQA GDWDAAYESA NAAVAQLSLN DKINIVTGIG WNAGGPCVGN
TAAIGSIGYP SLCLQDGPLG VRYGGSVTAF TPGIQAGSTW DRTLIKQRGQ FIGEEAKGCG
IHVMLGPAAG GLGKIPTGGR NWEGFGADPY LQGIATEETI LGFIAAGVQP TVKHYIVNEQ
ELNRETMSSN VDDRTMHELY LWPFADAVHA NVASIMCSYN KINGTWACEN DSILNGLAKE
ELGFRGYIMT DWNAQHSTVE SAVAGLDLTM PGSDYDGGSV LWGPALQQAV GSGSVSQDRV
DDMVTRILAS WYFYGQDQDY PPININANVQ GEHKDNVRAM ARDGIVLLKN DDNILPLQAP
GKLALVGSAA AAGNHASNNC ADRGCNEGAL GMGWGSGTAD YPYFVAPEDA ITERAQADGT
QVSTSASDST GNVGSVVSGA DAAIVFITAD SGEGYITVEN NVGDRVNLDP WHNGNQLVEA
VAGAADNVIV VVHSVGPLIL ESVLSNPSVK AIVWAGLPSQ ENGNALVDVL YGDVSPSGKL
PYTIAKAESD YGTQVVQGND DFSEGLFVDY RHFDAEEIEP QYEFGFGLSY TTFAYSDIAA
EGAPSSGPAT GDIIPGGRAD LWETVATVTA TVTNSGEIQG AEVAQLYVGY PESANTPPRQ
LRGFVKLPLD AGESAAATFE LRRRDLSIWD VASQEWTVPT GEFNITVGAS SRDLRLSTIL
TVA
//
