ID M7T3V2_EUTLA Unreviewed; 555 AA.
AC M7T3V2;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007};
DE EC=2.7.1.- {ECO:0000256|RuleBase:RU362007};
GN ORFNames=UCREL1_8535 {ECO:0000313|EMBL:EMR64511.1};
OS Eutypa lata (strain UCR-EL1) (Grapevine dieback disease fungus) (Eutypa
OS armeniacae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Diatrypaceae; Eutypa.
OX NCBI_TaxID=1287681 {ECO:0000313|EMBL:EMR64511.1, ECO:0000313|Proteomes:UP000012174};
RN [1] {ECO:0000313|Proteomes:UP000012174}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCR-EL1 {ECO:0000313|Proteomes:UP000012174};
RX PubMed=23723393; DOI=10.1128/genomeA.00228-13;
RA Blanco-Ulate B., Rolshausen P.E., Cantu D.;
RT "Draft genome sequence of the grapevine dieback fungus Eutypa lata UCR-
RT EL1.";
RL Genome Announc. 1:E0022813-E0022813(2013).
CC -!- SIMILARITY: Belongs to the hexokinase family.
CC {ECO:0000256|ARBA:ARBA00009225, ECO:0000256|RuleBase:RU362007}.
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DR EMBL; KB707053; EMR64511.1; -; Genomic_DNA.
DR RefSeq; XP_007796403.1; XM_007798212.1.
DR AlphaFoldDB; M7T3V2; -.
DR STRING; 1287681.M7T3V2; -.
DR KEGG; ela:UCREL1_8535; -.
DR eggNOG; KOG1369; Eukaryota.
DR HOGENOM; CLU_014393_4_1_1; -.
DR OMA; FPVEQTS; -.
DR OrthoDB; 5481886at2759; -.
DR UniPathway; UPA00109; UER00180.
DR Proteomes; UP000012174; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR GO; GO:0004396; F:hexokinase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0001678; P:intracellular glucose homeostasis; IEA:InterPro.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.40.367.20; -; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR001312; Hexokinase.
DR InterPro; IPR022673; Hexokinase_C.
DR InterPro; IPR022672; Hexokinase_N.
DR PANTHER; PTHR19443; HEXOKINASE; 1.
DR PANTHER; PTHR19443:SF24; HEXOKINASE YLR446W-RELATED; 1.
DR Pfam; PF00349; Hexokinase_1; 1.
DR Pfam; PF03727; Hexokinase_2; 1.
DR PRINTS; PR00475; HEXOKINASE.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS51748; HEXOKINASE_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU362007};
KW Glycolysis {ECO:0000256|RuleBase:RU362007};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU362007};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU362007};
KW Reference proteome {ECO:0000313|Proteomes:UP000012174};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU362007}.
FT DOMAIN 54..241
FT /note="Hexokinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00349"
FT DOMAIN 248..545
FT /note="Hexokinase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03727"
SQ SEQUENCE 555 AA; 60051 MW; 9D6FA8229992C156 CRC64;
MQPLTSAMTT LRRALLAAFK SFIHRHANNG HAVLPLRSLE DFLREAEERL LGPLDDDGLR
RFSEGLKTQF RERLQICGEN MLPSFNHLLP TGLEKGHYLA LDVGGSTLRV ALVELRGREA
SGRESEIVQI QTFKITPDIK ELEGMAFFDW LAARINEVMN KEPRSTPGPI PMGLAWSFPV
EQTSLGGGLL LGMGKGFLAT KGLLGQDLGE IIKFACKKQG LEVELGAIVN DSTAALLSQA
YVHASTHFGL ILGTGSNIAV HLPVSALSRS KYGNRPPAWF DTASHVIVNT EVSMFGKGVL
PLSRWDELLN ASHPRPEFQP LEHCCSGFYL GEICRLALIE AIESTGVLGG ELPPSLEKPY
SFDTETLSRI EADTSSTLET ATSYFVSKHP SASHQPNISD ITFIRNLASL ISRRAAALLA
AAVFALWELR HEAEAEDLAQ QQQQQQPHVT ETTRTATVKK GEVIVSVSET NIEEGGESVV
SSSPQPPPAT KVAFNGSVIE HYPQYRDNCQ DYLDGLLAQS SRPACAVDLV PAVESSLLGA
AVALASAVEA AAAEA
//
