ID   M7T4Q2_EUTLA            Unreviewed;       540 AA.
AC   M7T4Q2;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=Putative nadph oxidase protein {ECO:0000313|EMBL:EMR71577.1};
GN   ORFNames=UCREL1_1377 {ECO:0000313|EMBL:EMR71577.1};
OS   Eutypa lata (strain UCR-EL1) (Grapevine dieback disease fungus) (Eutypa
OS   armeniacae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Diatrypaceae; Eutypa.
OX   NCBI_TaxID=1287681 {ECO:0000313|EMBL:EMR71577.1, ECO:0000313|Proteomes:UP000012174};
RN   [1] {ECO:0000313|Proteomes:UP000012174}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCR-EL1 {ECO:0000313|Proteomes:UP000012174};
RX   PubMed=23723393; DOI=10.1128/genomeA.00228-13;
RA   Blanco-Ulate B., Rolshausen P.E., Cantu D.;
RT   "Draft genome sequence of the grapevine dieback fungus Eutypa lata UCR-
RT   EL1.";
RL   Genome Announc. 1:E0022813-E0022813(2013).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KB705622; EMR71577.1; -; Genomic_DNA.
DR   RefSeq; XP_007789328.1; XM_007791137.1.
DR   AlphaFoldDB; M7T4Q2; -.
DR   STRING; 1287681.M7T4Q2; -.
DR   KEGG; ela:UCREL1_1377; -.
DR   eggNOG; KOG0039; Eukaryota.
DR   HOGENOM; CLU_005646_3_0_1; -.
DR   OMA; FTFAKEH; -.
DR   OrthoDB; 367877at2759; -.
DR   Proteomes; UP000012174; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR   CDD; cd06186; NOX_Duox_like_FAD_NADP; 1.
DR   Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR   Gene3D; 2.40.30.10; Translation factors; 1.
DR   InterPro; IPR000778; Cyt_b245_heavy_chain.
DR   InterPro; IPR013112; FAD-bd_8.
DR   InterPro; IPR017927; FAD-bd_FR_type.
DR   InterPro; IPR013130; Fe3_Rdtase_TM_dom.
DR   InterPro; IPR013121; Fe_red_NAD-bd_6.
DR   InterPro; IPR039261; FNR_nucleotide-bd.
DR   InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR   PANTHER; PTHR11972:SF39; FAD-BINDING FR-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR11972; NADPH OXIDASE; 1.
DR   Pfam; PF08022; FAD_binding_8; 1.
DR   Pfam; PF01794; Ferric_reduct; 1.
DR   Pfam; PF08030; NAD_binding_6; 1.
DR   PRINTS; PR00466; GP91PHOX.
DR   SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR   SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR   PROSITE; PS51384; FAD_FR; 1.
PE   4: Predicted;
KW   Electron transport {ECO:0000256|ARBA:ARBA00022982};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000012174};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00023065}.
FT   TRANSMEM        20..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        59..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        158..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          227..350
FT                   /note="FAD-binding FR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51384"
SQ   SEQUENCE   540 AA;  61657 MW;  BC5D8E09ABB12D94 CRC64;
     MAGGMPLSTL VKKQFTGSKI IFHILFWGVH FGFFAYGWWK QNADVKLAAL NTLSWSVWLS
     RGAGLVLAID GTLILLPVCR TIVRALRPKI RFLPLDENLW FHRQVAFYNV ERTQIRPATA
     IQIHYTQPGG VTGHVMLLCM LLMYTTAHHR IRQQSFETFW YTHHLFIPFL LGLYTHAVGC
     FVRDTALPFS PFAGADFWEH CIGYQGWRWE LWAGGLYLAE RLYREIRAIR QTKITRVVRH
     PYDVVEIQFA KPSFKYKAGQ WLFLQVPSIS GYQWHPFTIT SCPYDPYVSV HVRQVGDFTR
     SLGDAVGAGA AQSKLYEGVD PMGMYEVALQ NGQQMPMLRI DGPYGAPAED VFENEIAILI
     GTGIGVTPWA SILKNIWHLR NSPNPPRRLR RVEFIWVCKD TGSFEWFQTL LSSLESQSTE
     AARIPGSNGV EFLKIHTYLT QKLDMDTQQN IVLNSVGADH DPLTELKART NFGRPNFQRM
     FEAMRDGILD RTYMNGLEGS MKTTVGVYFC GPSAAARDIQ KAAKAATSRE VHFRFWKEHF
//