ID M7T6K5_EUTLA Unreviewed; 583 AA.
AC M7T6K5;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Putative beta-xylosidase protein {ECO:0000313|EMBL:EMR65451.1};
GN ORFNames=UCREL1_7551 {ECO:0000313|EMBL:EMR65451.1};
OS Eutypa lata (strain UCR-EL1) (Grapevine dieback disease fungus) (Eutypa
OS armeniacae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Diatrypaceae; Eutypa.
OX NCBI_TaxID=1287681 {ECO:0000313|EMBL:EMR65451.1, ECO:0000313|Proteomes:UP000012174};
RN [1] {ECO:0000313|Proteomes:UP000012174}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCR-EL1 {ECO:0000313|Proteomes:UP000012174};
RX PubMed=23723393; DOI=10.1128/genomeA.00228-13;
RA Blanco-Ulate B., Rolshausen P.E., Cantu D.;
RT "Draft genome sequence of the grapevine dieback fungus Eutypa lata UCR-
RT EL1.";
RL Genome Announc. 1:E0022813-E0022813(2013).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865, ECO:0000256|RuleBase:RU361187}.
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DR EMBL; KB706863; EMR65451.1; -; Genomic_DNA.
DR RefSeq; XP_007795434.1; XM_007797243.1.
DR AlphaFoldDB; M7T6K5; -.
DR STRING; 1287681.M7T6K5; -.
DR KEGG; ela:UCREL1_7551; -.
DR eggNOG; ENOG502QZZ0; Eukaryota.
DR HOGENOM; CLU_016508_2_0_1; -.
DR OMA; NWELVSH; -.
DR OrthoDB; 1891044at2759; -.
DR Proteomes; UP000012174; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd18617; GH43_XynB-like; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR041542; GH43_C2.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR42812; BETA-XYLOSIDASE; 1.
DR PANTHER; PTHR42812:SF12; BETA-XYLOSIDASE-RELATED; 1.
DR Pfam; PF17851; GH43_C2; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361187};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361187};
KW Reference proteome {ECO:0000313|Proteomes:UP000012174};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..583
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004085319"
FT DOMAIN 347..554
FT /note="Beta-xylosidase C-terminal Concanavalin A-like"
FT /evidence="ECO:0000259|Pfam:PF17851"
FT ACT_SITE 33
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT ACT_SITE 213
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT SITE 149
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 583 AA; 64306 MW; 23C427882A011F29 CRC64;
MAYLRSSWLL RLLLLCGTAL AIKNPILPGF NPDPSILRVG DEYFIATSTF TVFPGIPIYK
SKDLANWELV SHALNDPAKV QLYGISTGNG ITGVWAPSLS YIDGLFYVTS MTMLGSDPST
RTWPRVWWVS SPDLVHWSDV VWGEPFGIDP HLFRDAAARS NKTYLTLMSP NNNYDRLWGI
SQCEVDLQSG NCGGVFRSLW NGTLPQDNST RPEGPKLFHK DDYYYLVLAE GGTSSGHRVT
IGRSKSPEGP WDAAPNNPLI YNGADPNLTV QSTGHATFVD TPGGDWYATM LARRNVDTWS
PLGRETFLVS IKWEDGWPIL NDGNPLLLSQ SIGTAPDQER PPPPFVDNFD GTDLDLGWYQ
LRTPYTTNYK LVSSTNASDS DSDSASESGV ILLPNVYTLG DRDTPAALIR KQTSLNMTFS
ATLLPTASGF GPRQSIGISA YINDHTHQDI GVRGCANATG LCLYMDFERN SPRPQDPPEE
TTEWALNATS IPEGLTLHIR AQPLTYKLGY SLGGGDDENP TWMTEFSSQW LTEAPSGFSV
FEGAMLVLFA SGNGDPWPFD APEVGFSRVR EVYYEENIPD YIT
//
