ID M7TQQ7_BOTF1 Unreviewed; 663 AA.
AC M7TQQ7;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE RecName: Full=Chromatin modification-related protein EAF3 {ECO:0000256|ARBA:ARBA00018505};
GN ORFNames=BcDW1_5454 {ECO:0000313|EMBL:EMR85896.1};
OS Botryotinia fuckeliana (strain BcDW1) (Noble rot fungus) (Botrytis
OS cinerea).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Sclerotiniaceae; Botrytis.
OX NCBI_TaxID=1290391 {ECO:0000313|EMBL:EMR85896.1, ECO:0000313|Proteomes:UP000012045};
RN [1] {ECO:0000313|Proteomes:UP000012045}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BcDW1 {ECO:0000313|Proteomes:UP000012045};
RX PubMed=23704180; DOI=10.1128/genomea.00252-13;
RA Blanco-Ulate B., Allen G., Powell A.L., Cantu D.;
RT "Draft genome sequence of Botrytis cinerea BcDW1, inoculum for noble rot of
RT grape berries.";
RL Genome Announc. 1:E0025213-E0025213(2013).
CC -!- SUBUNIT: Component of the NuA4 histone acetyltransferase complex.
CC {ECO:0000256|ARBA:ARBA00011353}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the MRG family. {ECO:0000256|ARBA:ARBA00009093}.
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DR EMBL; KB707879; EMR85896.1; -; Genomic_DNA.
DR AlphaFoldDB; M7TQQ7; -.
DR STRING; 1290391.M7TQQ7; -.
DR HOGENOM; CLU_027077_0_0_1; -.
DR Proteomes; UP000012045; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd18983; CBD_MSL3_like; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 1.10.274.30; MRG domain; 1.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR008676; MRG.
DR InterPro; IPR038217; MRG_C_sf.
DR InterPro; IPR026541; MRG_dom.
DR InterPro; IPR025995; Tudor-knot.
DR PANTHER; PTHR10880; MORTALITY FACTOR 4-LIKE PROTEIN; 1.
DR PANTHER; PTHR10880:SF15; MRG DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF05712; MRG; 1.
DR Pfam; PF11717; Tudor-knot; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR PROSITE; PS51640; MRG; 1.
PE 3: Inferred from homology;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 17..66
FT /note="Tudor-knot"
FT /evidence="ECO:0000259|Pfam:PF11717"
FT DOMAIN 477..649
FT /note="MRG"
FT /evidence="ECO:0000259|Pfam:PF05712"
FT REGION 84..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 272..301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 397..430
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..298
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 407..429
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 663 AA; 75410 MW; 72596507DC4689BE CRC64;
MAPSKSGPPV APYAKDEKVL CFHHDLLYEA KVLDTRPTED GSSWQCKIHY KGWKATWDDW
VPQDRVMKFN DDNKELAAQL HQEMKKMSQK PKSATSAGGK KIGGRTNGSD FGSGRGSEER
HASVAAQGGG RGGPRRNRDY DLEQMGPPIV PAVKAGAKRF AKKIGISASQ NKIQKPQVTN
AKEKTKAKTK VKAVAKAVVK AVNNLAVPSV NVRRSAREKR PKKPYDRSII DSGNLMITKP
KPMMNGKDPD WANPKSEHWN VDKFLKSDSM VPKTNLDARP PKDFQFISNN SIRNPETYRP
DKSNYFYKPK EKAAPVHPKL QAHIKKGTDT KPLRQWYADY EPGQINPIAG RLFDDNQLPP
PQLKRKRLFP LSYSEERIEE IMKPPPKKPR LILKNGLNKS APEKTAGKAV SKTSQKASLK
NNGTAASTGA EKRVQFEKEM MGSSEVRGER LIKTTKKMLP RILNSNIVME RRDFNYLQEE
NFHNRPSINL VIPDHIKAIL VDDWENVTKN QQLVPLPHKK SVDQILNDWL EFEKPKRPVG
SAQADILEEI VAGLKEYFER CLPRILLYRF ERQQHMDFRE LWDDDSYQQS SACDTYGAEH
LCRLLVTLPE LIAQTNMDLQ SVNRLREELS KLTNWIGKNA KDYFVNEYET PGAEYVDKAR
NPN
//
