ID   M7US60_BOTF1            Unreviewed;       820 AA.
AC   M7US60;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=Patatin-like phospholipase domain-containing protein {ECO:0000256|RuleBase:RU362055};
DE            EC=3.1.1.- {ECO:0000256|RuleBase:RU362055};
GN   ORFNames=BcDW1_1542 {ECO:0000313|EMBL:EMR89833.1};
OS   Botryotinia fuckeliana (strain BcDW1) (Noble rot fungus) (Botrytis
OS   cinerea).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Sclerotiniaceae; Botrytis.
OX   NCBI_TaxID=1290391 {ECO:0000313|EMBL:EMR89833.1, ECO:0000313|Proteomes:UP000012045};
RN   [1] {ECO:0000313|Proteomes:UP000012045}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BcDW1 {ECO:0000313|Proteomes:UP000012045};
RX   PubMed=23704180; DOI=10.1128/genomea.00252-13;
RA   Blanco-Ulate B., Allen G., Powell A.L., Cantu D.;
RT   "Draft genome sequence of Botrytis cinerea BcDW1, inoculum for noble rot of
RT   grape berries.";
RL   Genome Announc. 1:E0025213-E0025213(2013).
CC   -!- FUNCTION: Lipid hydrolase. {ECO:0000256|RuleBase:RU362055}.
CC   -!- FUNCTION: Probable lipid hydrolase. {ECO:0000256|ARBA:ARBA00002682}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU362055}; Single-
CC       pass membrane protein {ECO:0000256|RuleBase:RU362055}.
CC   -!- SIMILARITY: Belongs to the PLPL family.
CC       {ECO:0000256|RuleBase:RU362055}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KB707721; EMR89833.1; -; Genomic_DNA.
DR   AlphaFoldDB; M7US60; -.
DR   STRING; 1290391.M7US60; -.
DR   HOGENOM; CLU_009031_1_2_1; -.
DR   Proteomes; UP000012045; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004806; F:triglyceride lipase activity; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:UniProt.
DR   CDD; cd07230; Pat_TGL4-5_like; 1.
DR   Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 2.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR002641; PNPLA_dom.
DR   InterPro; IPR021771; Triacylglycerol_lipase_N.
DR   PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR   PANTHER; PTHR14226:SF10; TRIACYLGLYCEROL LIPASE 4-RELATED; 1.
DR   Pfam; PF11815; DUF3336; 1.
DR   Pfam; PF01734; Patatin; 1.
DR   SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR   PROSITE; PS51635; PNPLA; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU362055};
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963,
KW   ECO:0000256|RuleBase:RU362055};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098,
KW   ECO:0000256|RuleBase:RU362055}.
FT   DOMAIN          232..429
FT                   /note="PNPLA"
FT                   /evidence="ECO:0000259|PROSITE:PS51635"
FT   REGION          591..610
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          620..669
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          700..724
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          778..806
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   820 AA;  91721 MW;  27F0623860241B13 CRC64;
     MVLFGYLQTP QFCVVNNNNT TATSAKPSNA NEYGHDREKV SEPSVGLFGP ATRILRTGAD
     ILNNKLLQVR DGLTEEERSA LRKKEERIQI LNLRMKNAET MEVWRSAAKE LDLLEDNEAW
     KLDSLSTDFD AALIEARTKQ MDTARIDCDI KKMLTLVRTT LSRDLGGMGN IRLYKHSHVG
     TKVVIERYIE STLDTVRALV ENSKYTLPVG LETKDILEQV VYARQAFGRS ALLLSGGATF
     GMNHVGVLKA LFEARLLPRI ISGASAGSIV CAVLCARTDE EIPDVLKEFP HGDLAVFEEN
     GNEDGVLDRI RRLLTEGAWI DIKHLTRVMR ELLGDMTFQE AYNRSRRILN ICVSSASVYE
     LPRLLNYVTA PNVMIWSAVA ASCSVPLLFS AAELLMKNPL TGETSSWNPT PQRWIDGSVD
     NDLPMTRLAE MFNVNHFIVS QVNPHVIPFI AKDEEAIKDT VMKDGSGGPG WVYNLTHLAK
     AEALHRMQVL AELGVFPNLV TKCKSILSQK YSGDITILPE INFKDFPRIL KNPTTEFMEQ
     ACLSGERATW PKLSRVWNHC AVELELDAAV QKLRARVVFS PSEVNLRRLR AGEGSRQSSG
     MGRQRFDNGN LLLMSRDEDG EFSKQDGKRE NSSRPSLRAT ASVLDITKHK ERSHYTVHHS
     AQTTPRRTPR LGLENEMFSF PIPSKDMLYI KNQIRDLSSA GETTLSPSSS DADKGSQTDG
     STTELEAEEA IYGIASSTSD RQLDLFSRNQ PITAGTDRVL ATSPSIVRNG TEFIYSPTAM
     SPAEMRPREE RKSLTEPSSP DWSYKKMFHQ WKEDDMRDAA
//