ID M7UWC0_BOTF1 Unreviewed; 460 AA.
AC M7UWC0;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Putative transcription factor iws1 protein {ECO:0000313|EMBL:EMR88157.1};
GN ORFNames=BcDW1_3180 {ECO:0000313|EMBL:EMR88157.1};
OS Botryotinia fuckeliana (strain BcDW1) (Noble rot fungus) (Botrytis
OS cinerea).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Sclerotiniaceae; Botrytis.
OX NCBI_TaxID=1290391 {ECO:0000313|EMBL:EMR88157.1, ECO:0000313|Proteomes:UP000012045};
RN [1] {ECO:0000313|Proteomes:UP000012045}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BcDW1 {ECO:0000313|Proteomes:UP000012045};
RX PubMed=23704180; DOI=10.1128/genomea.00252-13;
RA Blanco-Ulate B., Allen G., Powell A.L., Cantu D.;
RT "Draft genome sequence of Botrytis cinerea BcDW1, inoculum for noble rot of
RT grape berries.";
RL Genome Announc. 1:E0025213-E0025213(2013).
CC -!- FUNCTION: Transcription factor involved in RNA polymerase II
CC transcription regulation. May function in both SPT15/TBP post-
CC recruitment and recruitment steps of transcription.
CC {ECO:0000256|ARBA:ARBA00037349}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00649}.
CC -!- SIMILARITY: Belongs to the IWS1 family.
CC {ECO:0000256|ARBA:ARBA00037992}.
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DR EMBL; KB707799; EMR88157.1; -; Genomic_DNA.
DR AlphaFoldDB; M7UWC0; -.
DR STRING; 1290391.M7UWC0; -.
DR HOGENOM; CLU_045275_1_0_1; -.
DR Proteomes; UP000012045; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR InterPro; IPR017923; TFIIS_N.
DR PANTHER; PTHR46010; PROTEIN IWS1 HOMOLOG; 1.
DR PANTHER; PTHR46010:SF1; PROTEIN IWS1 HOMOLOG; 1.
DR Pfam; PF08711; Med26; 1.
DR SUPFAM; SSF47676; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR PROSITE; PS51319; TFIIS_N; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00649}.
FT DOMAIN 272..349
FT /note="TFIIS N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51319"
FT REGION 1..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 373..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 412..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..116
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..180
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 373..391
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 460 AA; 51715 MW; 7C1DEF7F4FF7427C CRC64;
MSDSDLDSKP TTPLPEAGND AGDPNRPISQ ERDTPEPPVA NPDLDMDDLD NAEDGGAGSD
NESDLSDVDE ANFDDFDASK VALDERPMVG IDEDIAKTLK ASKRKRAEGE AKKPKEGKRD
KKKRPRRDSD EDPDGMEIDG KRIRKPKRVE GEGKDRDRTK ERRKATPEPE NDENLTPDER
RRRALDKAMD AALKNPNKRR RKKDEVDLEE AFDDEIAALK LRMEEACQAD NAARDANLPA
TRKLEMLPEV VALLNRNTIQ HSIVDPDTNF LQSVKFFLEP LNDGSLPAYN IQRDLFQALA
RLPIEKEALL SSGIGKVVLY YTKSKRPEIQ IKRIAERLLG EWSRPILKRS DDYKKRKVAT
KEYDFQAAQL AIRPSGSQSS QMPSSQRTQL TARDIERQRL LAPKVISNRA RMETSNTSYS
IAPRSNFDPS RGLDPSSRPI GAGGVDAFRK MTAKQGKKRS
//
