ID M7ZBH2_TRIUA Unreviewed; 531 AA.
AC M7ZBH2;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Flavonoid 3',5'-hydroxylase {ECO:0000313|EMBL:EMS57417.1};
GN ORFNames=TRIUR3_03008 {ECO:0000313|EMBL:EMS57417.1};
OS Triticum urartu (Red wild einkorn) (Crithodium urartu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4572 {ECO:0000313|EMBL:EMS57417.1};
RN [1] {ECO:0000313|EMBL:EMS57417.1, ECO:0000313|Proteomes:UP000015106}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. G1812 {ECO:0000313|Proteomes:UP000015106};
RX PubMed=23535596; DOI=10.1038/nature11997;
RA Ling H.Q., Zhao S., Liu D., Wang J., Sun H., Zhang C., Fan H., Li D.,
RA Dong L., Tao Y., Gao C., Wu H., Li Y., Cui Y., Guo X., Zheng S., Wang B.,
RA Yu K., Liang Q., Yang W., Lou X., Chen J., Feng M., Jian J., Zhang X.,
RA Luo G., Jiang Y., Liu J., Wang Z., Sha Y., Zhang B., Wu H., Tang D.,
RA Shen Q., Xue P., Zou S., Wang X., Liu X., Wang F., Yang Y., An X., Dong Z.,
RA Zhang K., Zhang X., Luo M.C., Dvorak J., Tong Y., Wang J., Yang H., Li Z.,
RA Wang D., Zhang A., Wang J.;
RT "Draft genome of the wheat A-genome progenitor Triticum urartu.";
RL Nature 496:87-90(2013).
RN [2] {ECO:0000313|EnsemblPlants:TuG1812G0700003431.01.T01}
RP IDENTIFICATION.
RG EnsemblPlants;
RL Submitted (JUN-2022) to UniProtKB.
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR EMBL; KD145202; EMS57417.1; -; Genomic_DNA.
DR AlphaFoldDB; M7ZBH2; -.
DR STRING; 4572.M7ZBH2; -.
DR EnsemblPlants; TuG1812G0700003431.01.T01; TuG1812G0700003431.01.T01; TuG1812G0700003431.01.
DR Gramene; TuG1812G0700003431.01.T01; TuG1812G0700003431.01.T01; TuG1812G0700003431.01.
DR eggNOG; KOG0156; Eukaryota.
DR OMA; LWRWRFD; -.
DR OrthoDB; 2900138at2759; -.
DR Proteomes; UP000015106; Unassembled WGS sequence.
DR GO; GO:0052722; F:fatty acid in-chain hydroxylase activity; IEA:EnsemblPlants.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen; IEA:EnsemblPlants.
DR GO; GO:0048653; P:anther development; IEA:EnsemblPlants.
DR GO; GO:0002933; P:lipid hydroxylation; IEA:EnsemblPlants.
DR GO; GO:0051792; P:medium-chain fatty acid biosynthetic process; IEA:EnsemblPlants.
DR GO; GO:0080110; P:sporopollenin biosynthetic process; IEA:EnsemblPlants.
DR CDD; cd20618; CYP71_clan; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR47949:SF3; CYTOCHROME P450 703A2; 1.
DR PANTHER; PTHR47949; CYTOCHROME P450 703A2-RELATED-RELATED; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Metal-binding {ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW Reference proteome {ECO:0000313|Proteomes:UP000015106};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..531
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015096596"
SQ SEQUENCE 531 AA; 60000 MW; C2097954A77FC6BC CRC64;
MDPFLLSIIL CSCIFAAVSW KKLNGMRLRL PPGPPRWPIF GNLLQLSPLP HKDFARFCTK
YGPLVYLRLG TIDAITTDDP EVIREILIRQ DEVFASRPRT LAAVHLAYGC GDVALAPLGP
NWKRMRRVCM EHLLTTRRLE SFAAHRAEEA EHLCEFVWAK SQSGKPVNLR EVLGAFSMNN
VTRMLLGKQY FGLQSAGPGE AMEFMHITHE LFFLLGLIYL GDYLPAWRWL DPYGCEKKMR
EVEKKVDDFH QKIIDEHRKA RDVRKSGASL DDDGDDSKEG MDFVDVLLSL PGENGNEHMD
DVEIKALMQD MIAAATDTSS VTNEWVMAEV IKNPRVLRKI QEELDAVVGT SRMVVEADLP
HLTYLRCVVR ESFRMHPAGP FLIPHESLKA TTIMGYDIPA QTRIFINTHA LGRNPRIWDD
VDEFRPERHL PADGGRVEIS HLPDFKILPF SAGKRKCPGA PLGVILVLMA LARLFHCFDW
SPPDGLRPED IDTDEVYGMT MPKAKPLIAA AQPRLPPQMY GSCPSHGMQM Q
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