ID M7ZEC3_TRIUA Unreviewed; 1043 AA.
AC M7ZEC3;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Putative disease resistance RPP8-like protein 4 {ECO:0000313|EMBL:EMS61533.1};
GN ORFNames=TRIUR3_13785 {ECO:0000313|EMBL:EMS61533.1};
OS Triticum urartu (Red wild einkorn) (Crithodium urartu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4572 {ECO:0000313|EMBL:EMS61533.1};
RN [1] {ECO:0000313|EMBL:EMS61533.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23535596; DOI=10.1038/nature11997;
RA Ling H.Q., Zhao S., Liu D., Wang J., Sun H., Zhang C., Fan H., Li D.,
RA Dong L., Tao Y., Gao C., Wu H., Li Y., Cui Y., Guo X., Zheng S., Wang B.,
RA Yu K., Liang Q., Yang W., Lou X., Chen J., Feng M., Jian J., Zhang X.,
RA Luo G., Jiang Y., Liu J., Wang Z., Sha Y., Zhang B., Wu H., Tang D.,
RA Shen Q., Xue P., Zou S., Wang X., Liu X., Wang F., Yang Y., An X., Dong Z.,
RA Zhang K., Zhang X., Luo M.C., Dvorak J., Tong Y., Wang J., Yang H., Li Z.,
RA Wang D., Zhang A., Wang J.;
RT "Draft genome of the wheat A-genome progenitor Triticum urartu.";
RL Nature 496:87-90(2013).
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KD094591; EMS61533.1; -; Genomic_DNA.
DR AlphaFoldDB; M7ZEC3; -.
DR STRING; 4572.M7ZEC3; -.
DR eggNOG; KOG4658; Eukaryota.
DR OMA; WNGNINT; -.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd06222; RNase_H_like; 1.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR044730; RNase_H-like_dom_plant.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR PANTHER; PTHR23155:SF906; NB-ARC DOMAIN CONTAINING PROTEIN, EXPRESSED; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF13456; RVT_3; 1.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614}.
FT DOMAIN 12..96
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 207..365
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT DOMAIN 898..1012
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|Pfam:PF13456"
SQ SEQUENCE 1043 AA; 118780 MW; 455AB5481E9242AD CRC64;
MAGIMVSAST GVMNYLLGKL TTLVGKEFTR LKNLRKEVRF INNELISMKY ALDGLSDLDE
LDPQTKRWRD MVREMSYEIE DIIDDFMQSI GENDRTTGLV SNTVRRLKTL RDRHRIAGQI
EEVKQLVLET SERQRRYELR IPPSSNVDID PRVTALYTEV ADLVGIEGPA NELVSWLMDE
EKKLKAVSIV GFGGLGKTTE TSIHTCESRL IEMLREHLQT KRYLIIIDDI WDISAWNIIK
CVFSKNDLAS RVVVTTRKQD AAMTCCSRDC ILQMKPLTNE DSTRLFFGRV FGSKEACPPQ
LRDISVEILK KCGGLPLAVI SISSMLANKN CNQKERWEYV QDSMGSESNH MLDGMRQILN
LSYKDLPPYL KTCLLYLGMY PEDYQIERSN LERQWMAEEF DKRGSVTKCK VHDMLLNLIL
IKSAQENFLT IVDDPHAFTR LQCKVRRLSI RLDGASNGRE IVSTNNSMSQ VRSIMFFGSS
QITPPLSEFK FLRVVHIDLD DAEVDLTGLC KLYQLRYLCI SDGCSYQLPT QIRVLQHLET
LELFSCDRVP SDIIHLPRLM FLKAWTRLPD GIGNMKSLRH LFGFDFTLYK LDNIRGLGEL
TNLKFLYLTC GIRKDDWERR MDALCSSLGN LCHLENLFVD LIGCIDGFMP LFPPPTHYRL
ERLIMQWRCW FSRVPSWMGE LHNLCQLKFK VGQLLTDGVG ILAELPALTH LDVETGKTTN
KVISIERGAF PALKSFKLLL SSALHLTFQA GAMPRLQRLK LKFNVHGSEQ IGAAPAGLEQ
LLALEELTAK ICCHRASESD KRSADSDLRS AIDMFPSHLL VKVSYEEVFF ERGYIWRVGN
GQNIDIWVDA WIPKCADRKV STPRGNHLIS WVADFIDPIS NEWDVELFGQ RISWNGNINT
LRGTVGAVLR DDRGKFIAGA NEKIDWCADI LAAEALALRY GLSLAQRIGC NRLVINSDNL
EVIETMNNGG GHAIAAAVIF DDCYYLACDF PISRFEHCNR EANKVAHELA RLARFSATYD
WFEEVLNEIV NFLTDDVSIL SNE
//
