ID M8A2U3_TRIUA Unreviewed; 788 AA.
AC M8A2U3;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Uncharacterized membrane protein C2G11.09 {ECO:0000313|EMBL:EMS66677.1};
GN ORFNames=TRIUR3_21726 {ECO:0000313|EMBL:EMS66677.1};
OS Triticum urartu (Red wild einkorn) (Crithodium urartu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4572 {ECO:0000313|EMBL:EMS66677.1};
RN [1] {ECO:0000313|EMBL:EMS66677.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23535596; DOI=10.1038/nature11997;
RA Ling H.Q., Zhao S., Liu D., Wang J., Sun H., Zhang C., Fan H., Li D.,
RA Dong L., Tao Y., Gao C., Wu H., Li Y., Cui Y., Guo X., Zheng S., Wang B.,
RA Yu K., Liang Q., Yang W., Lou X., Chen J., Feng M., Jian J., Zhang X.,
RA Luo G., Jiang Y., Liu J., Wang Z., Sha Y., Zhang B., Wu H., Tang D.,
RA Shen Q., Xue P., Zou S., Wang X., Liu X., Wang F., Yang Y., An X., Dong Z.,
RA Zhang K., Zhang X., Luo M.C., Dvorak J., Tong Y., Wang J., Yang H., Li Z.,
RA Wang D., Zhang A., Wang J.;
RT "Draft genome of the wheat A-genome progenitor Triticum urartu.";
RL Nature 496:87-90(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
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DR EMBL; KD029004; EMS66677.1; -; Genomic_DNA.
DR AlphaFoldDB; M8A2U3; -.
DR STRING; 4572.M8A2U3; -.
DR eggNOG; KOG1134; Eukaryota.
DR OMA; LWTHCLA; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF117; CSC1-LIKE PROTEIN RXW8; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023303};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 5..92
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 137..296
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 307..574
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
SQ SEQUENCE 788 AA; 88753 MW; 8A9B7037D2507252 CRC64;
MKISALLTSA GINIGLCVLF LSLYSVLRKQ PANVRVYFGR RISEEHSRLR EAFILERFVP
STGWIVKALR YTEEELLAAA GLDAVAFNRM LVFRLWVHCL VLYIISGVAC ILLYLEYRHI
ARLRLLHLKR ATPNPGQFTV LVRGIPKITK ESCSSAVDDF FTKYHGSSYL FHQVVYKVGK
VQKIMTGAKK ACRKLKHFTD TTVDQSCKAI TYRCCLCGAS SNSFHLLPTD EVVPSRGKAD
LDDSSLNMDN EECAAAFVFF KTRYGALVAS DVLQTSNPTK WVTDPAPEPN DVYWSNIWLP
YKQLWIRRIA TLLGSIVFML LFLAPVTFIN GLSQLDQLQK RLPFLNGILK QPHHMVQLIT
GYLPSVILQI FLYSVAPIMM LFSTLEGPVS HSERKRSACC KVLYFLIWNV FFVNVVSGTV
LKQLDFFSSP KDIPVQLAKV IPGQASFFIT YVLTSGWASL SSELMQLFGL IYNFIRKYVL
RMKEDTEFVP SFPYHTEVPK VLLFGLLGFT CSVLAPLILP FLLVYFFLGY VVYRNQLLNV
YRTRYDTGGL YWPIIHNTVI FSLVLTQIIC LGVFGLKVSP VAAGFTIPLI IFTLLFNQYC
RTRLLPLFST FPAQCKLGNN SGAELYCHFL TGDYYPCFVD RCVPQVQNLI DMDREDELSG
RMEHIHQRLH TAYCQFPDSE DIQLEEIRTV GNDEDVGGCS SGGSNGKGSP GEFNGKGSSD
ESNGKGSPGE FNGKGGSDES NGKETLQEQQ QPRRDLSHPT LKGLPVSRLQ NAVRCVTFLI
RLQKRGLS
//
