ID M8B327_TRIUA Unreviewed; 1050 AA.
AC M8B327;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Disease resistance protein RPM1 {ECO:0000313|EMBL:EMS67964.1};
GN ORFNames=TRIUR3_13082 {ECO:0000313|EMBL:EMS67964.1};
OS Triticum urartu (Red wild einkorn) (Crithodium urartu).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Triticodae; Triticeae; Triticinae; Triticum.
OX NCBI_TaxID=4572 {ECO:0000313|EMBL:EMS67964.1};
RN [1] {ECO:0000313|EMBL:EMS67964.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23535596; DOI=10.1038/nature11997;
RA Ling H.Q., Zhao S., Liu D., Wang J., Sun H., Zhang C., Fan H., Li D.,
RA Dong L., Tao Y., Gao C., Wu H., Li Y., Cui Y., Guo X., Zheng S., Wang B.,
RA Yu K., Liang Q., Yang W., Lou X., Chen J., Feng M., Jian J., Zhang X.,
RA Luo G., Jiang Y., Liu J., Wang Z., Sha Y., Zhang B., Wu H., Tang D.,
RA Shen Q., Xue P., Zou S., Wang X., Liu X., Wang F., Yang Y., An X., Dong Z.,
RA Zhang K., Zhang X., Luo M.C., Dvorak J., Tong Y., Wang J., Yang H., Li Z.,
RA Wang D., Zhang A., Wang J.;
RT "Draft genome of the wheat A-genome progenitor Triticum urartu.";
RL Nature 496:87-90(2013).
CC -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC {ECO:0000256|ARBA:ARBA00008894}.
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DR EMBL; KD012420; EMS67964.1; -; Genomic_DNA.
DR AlphaFoldDB; M8B327; -.
DR STRING; 4572.M8B327; -.
DR eggNOG; KOG4658; Eukaryota.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR CDD; cd14798; RX-CC_like; 1.
DR Gene3D; 1.20.5.4130; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038005; RX-like_CC.
DR InterPro; IPR041118; Rx_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR23155:SF1013; DISEASE RESISTANCE PROTEIN PIK6-NP; 1.
DR PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR Pfam; PF00931; NB-ARC; 2.
DR Pfam; PF18052; Rx_N; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821}.
FT DOMAIN 12..86
FT /note="Disease resistance N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18052"
FT DOMAIN 190..253
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
FT DOMAIN 385..455
FT /note="NB-ARC"
FT /evidence="ECO:0000259|Pfam:PF00931"
SQ SEQUENCE 1050 AA; 116502 MW; B8CF70B31DC59253 CRC64;
MELVVGASEA TMKSLLAKLG GLLAQEYTLI TGVNGDLQYI NDELATMQSF LRDVTTVGGG
HGHRMKDWMK QIRDITYDIE DCIDDSADRL HGVPTDTCCY FLVNSIYEIL TWWPRRQVAT
RISILKMRAQ QIAERRDRYG VNNPYCPGTD GSGAGSSTVV GFDAADNQDE SRQLVAVKDP
VGVEEHMGDL DKRVTYIVGF GGVGKTAIAT ALYRKFGDRF GHRAMVTVSQ SSDLETILRS
IENQVKPPTS NQQKQGGSGE SRFAAAVKGA RDQVSRGTSA IMAKCCSSGA SEEDRTKLDL
LKNDLANNLK ENRNSKALLT FCGAALNYSL QVFLPRFTCL ALVLIEQRNN FNDSALFFLM
KSLQILKEIA ATAGHSLSAP FLFGSYLILI DDVWSATTLD NIINALPNNK DSRIIVTTRF
HAVATTRREG DIRKVKGLAD KESEELFRQA FHESKGSKYV IKGPQAPGTT SKIEEADFAH
NIANTDSDKP VKLFEPSVSE PSDSKDVTSP DKVWKMCGGL PLAIVTMAGH VACNPRRTQD
EWLDLCCSPF SESGKDHGKD GGKEITQEEV GRIVSHCYND MPAEIKTCSL YLSIFPKGQK
ISRKRLTRRW IAESFVCEKQ GLSVEDVAET YFNHLIRRKI IRPVEHSSNG KVKKFIVHDM
VLEHIVAKAS EENFITVVGG NWLMQPPSTK VRRLSLQGGD SKHAKDAEKM NLSHVRSVTM
FGSLNQMSSH SFKFGIVQVL DLEGCTGLKG HHTEEICKMV LLKYLSLRRT DTKKLPKTIG
KLENLETLDI RETNVVELPK TVCQLERLVN ILGGDKRTRK ALKIPEELSK KKKMKSLRIL
SGIEITGGSA DLHHLTELRK LAIYKLKTIG EDATFKDLSS SIEYLGGHSL RTFVVDGESS
EFIRSLDDLS TPPKFLVALE LSGKIMKVPS WITELTALTK VTLSVTAFWT DNLKVLSNLE
VLFCLSFTLM AANQDAETLT ILAENKLHSN GEVIVPDGGF KSLKLLRFSA PLLPLLSFSR
DAMPGLERLE LRFSPRRTQS CAYDIGGQRR
//
