ID   M8BTP9_AEGTA            Unreviewed;       424 AA.
AC   M8BTP9;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Vacuolar-processing enzyme {ECO:0000313|EnsemblPlants:EMT06287};
OS   Aegilops tauschii (Tausch's goatgrass) (Aegilops squarrosa).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX   NCBI_TaxID=37682 {ECO:0000313|EnsemblPlants:EMT06287};
RN   [1] {ECO:0000313|EnsemblPlants:EMT06287}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the peptidase C13 family.
CC       {ECO:0000256|ARBA:ARBA00009941}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; M8BTP9; -.
DR   EnsemblPlants; EMT06287; EMT06287; F775_27985.
DR   ExpressionAtlas; M8BTP9; baseline.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0051603; P:proteolysis involved in protein catabolic process; IEA:InterPro.
DR   CDD; cd21115; legumain_C; 1.
DR   Gene3D; 1.10.132.130; -; 1.
DR   Gene3D; 3.40.50.1460; -; 1.
DR   InterPro; IPR043577; AE.
DR   InterPro; IPR048501; Legum_prodom.
DR   InterPro; IPR046427; Legumain_prodom_sf.
DR   InterPro; IPR001096; Peptidase_C13.
DR   PANTHER; PTHR12000:SF56; -; 1.
DR   PANTHER; PTHR12000; HEMOGLOBINASE FAMILY MEMBER; 1.
DR   Pfam; PF20985; Legum_prodom; 1.
DR   Pfam; PF01650; Peptidase_C13; 1.
DR   PIRSF; PIRSF500139; AE; 1.
DR   PIRSF; PIRSF019663; Legumain; 1.
DR   PRINTS; PR00776; HEMOGLOBNASE.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          311..407
FT                   /note="Legumain prodomain"
FT                   /evidence="ECO:0000259|Pfam:PF20985"
FT   ACT_SITE        106
FT                   /evidence="ECO:0000256|PIRSR:PIRSR019663-1"
FT   ACT_SITE        148
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR019663-1"
SQ   SEQUENCE   424 AA;  46623 MW;  394BCBDE881E0834 CRC64;
     MSQVRADICH AYQILKTGGL KDENIIVFMY DDIAHNLENP RPGVIINHPQ GGDVYAGVPK
     DYTGKEVNVK NLFAVLLGNK TAVSGGSGKV VDSGPNDHIF VFYSDHGGPG VIGMPTYPYV
     YGDDLVDVLK KKHAAGTYKS LVFYLEACEA GSVFEGLLPN DIGVYATTAS NAEESSWGTY
     CPGEYPSPPS EYDTCLGDLY SISWMEDSDV HNLRTESLKQ QYDLVKKRTA AQDSYSYGSH
     VMQYGSLDLN DQHLFLYIGS NPANDNTTFV EDNSLPSFSR AVNQRDADLV YFWRKYQKLA
     ESSTEKNDAR KQLLEMMGHR SHIDNSVELI GNLLFGFADG PMVLKTVRPA GEPLADDWSC
     LKSMVRAFES QCGSLAQYGM KHMRSFANIC NAGILPEAMV KMAAQACTSI PTNPWSATHN
     GFSA
//