ID   M8BU35_AEGTA            Unreviewed;       500 AA.
AC   M8BU35;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   SubName: Full=Disease resistance protein RPP8 {ECO:0000313|EnsemblPlants:EMT28550};
OS   Aegilops tauschii (Tausch's goatgrass) (Aegilops squarrosa).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX   NCBI_TaxID=37682 {ECO:0000313|EnsemblPlants:EMT28550};
RN   [1] {ECO:0000313|EnsemblPlants:EMT28550}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the disease resistance NB-LRR family.
CC       {ECO:0000256|ARBA:ARBA00008894}.
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DR   AlphaFoldDB; M8BU35; -.
DR   EnsemblPlants; EMT28550; EMT28550; F775_04976.
DR   ExpressionAtlas; M8BU35; baseline.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:InterPro.
DR   GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR   CDD; cd14798; RX-CC_like; 1.
DR   Gene3D; 1.20.5.4130; -; 1.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038005; RX-like_CC.
DR   InterPro; IPR041118; Rx_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR   PANTHER; PTHR23155:SF912; NB-ARC DOMAIN CONTAINING PROTEIN, EXPRESSED; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF18052; Rx_N; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614}.
FT   DOMAIN          6..88
FT                   /note="Disease resistance N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF18052"
FT   DOMAIN          167..388
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
SQ   SEQUENCE   500 AA;  56694 MW;  CBE9EF0D6949159F CRC64;
     MVGTGALGSV IVKLATLLGD GHTMLKSVRK DIAFLERELR TMQILVNMLA GMEGLDKRAM
     GCMGSMRDLG HDMEGCIDRF MLRLDENDME MEAVPTFPRS TARQLKTMFA RHGVGAQIKK
     LKARVVEEGE RRRRLNLDNY VSMTVDPRLA PLHGVAKDLV AIDGPRNEVV SLLTEESVDL
     KVVAVVGGAG LGKTTLAMEA YRKIGRHFQC RASVSVSRTL DRDKLLKDLL SQIDQAAFHD
     CQSERWDKDQ LIRRIRHILT GKRYFLVVDD VWKEQDWKFV KGVFPDNHNG SRIIVTTRIA
     NVAKSTCSNS GGQLYQMLPL NYIDSRRLFF KRIFHSDNSC PPQLEKISAR ILRKCGGLPL
     AIITIAKLLS NKHQTPDEWE RLQGSIGAGL SYKSDNHGNG MGHISLLSYW DLPHHLKTCL
     LYLCVYPEGE YISCEEVKWK WILEGFIATR RGNLYQEAES CFNELVNRSM IQLVDVDDDN
     FERYCQVHVM VHDLLISLSD
//