ID   M8C372_AEGTA            Unreviewed;       457 AA.
AC   M8C372;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=Cystathionine gamma-synthase, chloroplastic {ECO:0000313|EnsemblPlants:EMT09613};
OS   Aegilops tauschii (Tausch's goatgrass) (Aegilops squarrosa).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX   NCBI_TaxID=37682 {ECO:0000313|EnsemblPlants:EMT09613};
RN   [1] {ECO:0000313|EnsemblPlants:EMT09613}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|RuleBase:RU362118};
CC   -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC       {ECO:0000256|RuleBase:RU362118}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; M8C372; -.
DR   SMR; M8C372; -.
DR   EnsemblPlants; EMT09613; EMT09613; F775_22576.
DR   OMA; RFVYSRY; -.
DR   GO; GO:0003962; F:cystathionine gamma-synthase activity; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR   GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR   CDD; cd00614; CGS_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR044639; CGS1/2.
DR   InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR43379:SF3; CYS_MET METABOLISM PLP-DEPENDENT ENZYME FAMILY PROTEIN; 1.
DR   PANTHER; PTHR43379; CYSTATHIONINE GAMMA-SYNTHASE; 1.
DR   Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR   PIRSF; PIRSF001434; CGS; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00868; CYS_MET_METAB_PP; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR001434-2}.
FT   MOD_RES         273
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ   SEQUENCE   457 AA;  49579 MW;  80244C317BC799FF CRC64;
     MAPTAKASST KQHRLLRARR SSSKRTAALS PEALLGATLP GVHHRFVPVL QQDDAVATGP
     TRDAALSDET LAVHAGEKMG GMVGTDSIAT PIVSGTTHWF KSSRNLIAFK EGRRHSFEYG
     RYSNPTVKVL EDKISALERA ESTLVTSSGM NAIVATLLAL VPAGAGHVVT TTECYSEARA
     FIRDKLSKMG IKVTFVELND MGTLKAVLDQ GNVTLFYTDS PTNPHLKCID IKLVAELCHR
     KGALVCIDST LASPINQKPL TLGADIVVHS ATKYIAGHHD VMAGCISGSK DLISRIRAWH
     HDLGGAISPD AAYMIIRGLK TMALRVETQN HTALRMARLL ENHPKIEQVY YPGLLSSPWH
     DIAKRQMTGF GGVISFEVAS DLHGVMMFVD ALEIPFIATS LGGCESLVQQ PAVMSFWGQS
     GEEKAKNGIK DNLVRFSFGI ENFEDLRDDI LQALEKI
//