ID M8D839_9BACL Unreviewed; 339 AA.
AC M8D839;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein {ECO:0000259|Pfam:PF01073};
GN ORFNames=I532_12294 {ECO:0000313|EMBL:EMT52434.1};
OS Brevibacillus borstelensis AK1.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX NCBI_TaxID=1300222 {ECO:0000313|EMBL:EMT52434.1, ECO:0000313|Proteomes:UP000012081};
RN [1] {ECO:0000313|EMBL:EMT52434.1, ECO:0000313|Proteomes:UP000012081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AK1 {ECO:0000313|EMBL:EMT52434.1,
RC ECO:0000313|Proteomes:UP000012081};
RA Rajan I., PoliReddy D., Sugumar T., Rathinam K., Alqarawi S., Khalil A.B.,
RA Sivakumar N.;
RT "Assembly of a new bacterial strain Brevibacillus borstelensis AK1.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC {ECO:0000256|ARBA:ARBA00009219}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMT52434.1}.
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DR EMBL; APBN01000004; EMT52434.1; -; Genomic_DNA.
DR RefSeq; WP_003388544.1; NZ_APBN01000004.1.
DR AlphaFoldDB; M8D839; -.
DR STRING; 1300222.I532_12294; -.
DR GeneID; 72735576; -.
DR PATRIC; fig|1300222.3.peg.2566; -.
DR OrthoDB; 9811743at2; -.
DR Proteomes; UP000012081; Unassembled WGS sequence.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR PANTHER; PTHR43245:SF51; SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2; 1.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000012081}.
FT DOMAIN 7..256
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
SQ SEQUENCE 339 AA; 38269 MW; DC33CB1718A4DF8A CRC64;
MKNRRVLVTG GTGFLGQKLA RRLHEQGAEV TVLGRNKRVG EALQKEGIRF VCTDITDQKA
VRDVCYGKQI VIHAAAFSSP WGRYRDMYAA NVEGTRHVIE GCRQHNVERL IHVSTPSLYF
AFEDRLGIKE SDPLPQRFAN EYAETKFLAE REVDNAFENG LATITIRPRA LFGPGDNAIL
PRLIRANKNR FVPIIEGGRA VIDLTYVDNV VDALLLCMDS SEKTLGKVYN ITNGEPVMLI
DVLKSVFAKL DMPLNSKEVS YRQAYGIASV LELLSRTLLA YREPMLTRYT VGVLAKSQTL
DITRAREELG YEPRVGLQEG IEIFANWWRQ EHERNTDPA
//
