ID M9M4I6_PSEA3 Unreviewed; 539 AA.
AC M9M4I6;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=G-protein alpha subunit {ECO:0000313|EMBL:GAC75335.1};
GN ORFNames=PANT_15d00026 {ECO:0000313|EMBL:GAC75335.1};
OS Pseudozyma antarctica (strain T-34) (Yeast) (Candida antarctica).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Moesziomyces.
OX NCBI_TaxID=1151754 {ECO:0000313|EMBL:GAC75335.1, ECO:0000313|Proteomes:UP000011976};
RN [1] {ECO:0000313|Proteomes:UP000011976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T-34 {ECO:0000313|Proteomes:UP000011976};
RX PubMed=23558529; DOI=10.1128/genomea.00064-13;
RA Morita T., Koike H., Koyama Y., Hagiwara H., Ito E., Fukuoka T., Imura T.,
RA Machida M., Kitamoto D.;
RT "Genome sequence of the basidiomycetous yeast Pseudozyma antarctica T-34, a
RT producer of the glycolipid biosurfactants mannosylerythritol lipids.";
RL Genome Announc. 1:E0006413-E0006413(2013).
CC -!- SIMILARITY: Belongs to the G-alpha family.
CC {ECO:0000256|ARBA:ARBA00005804}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DF196781; GAC75335.1; -; Genomic_DNA.
DR AlphaFoldDB; M9M4I6; -.
DR STRING; 1151754.M9M4I6; -.
DR OrthoDB; 1438431at2759; -.
DR Proteomes; UP000011976; Unassembled WGS sequence.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF302; GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-8 SUBUNIT-RELATED; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000011976};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 154..179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..179
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 539 AA; 60498 MW; 6A808710FDAE0D4D CRC64;
MSPTVSSRDI RRMQSGNMTP NDRDPLSLAL RPPSNETAAQ RQVRLHQEKQ AKLRSDEIDK
LLKRTEASTS NSASLEAKKG RVYKMVLLGQ AGAGKTTVLK QMRLLYDAEA HERERKGWTS
IVVLNLTASV RVLLQTLERY HQGRAERKSL ELARLESPAS PVSPHSTHNA VSPSSATESV
IETASARALG PSNTAWERHL PKIVQLESKL RGQLGAFGEE APVNDPESRM MTTRRTKMGD
KSLLLLRPGW QERLFTYARR SLSLGAGGRN YMQEQTHRDE EAGGDDESDA LVLLRSIQAE
VTALWDDDVR CRALRKRGVF LDGQSEAATS YFLEAYARIV APGYSPSDED ILHSRVRTLG
VTEDVFRIDR SLTYRVFDVG GSRSQRAAWV PFLDDAQSII FLAPLSAFDQ PLVEDPSTNR
LADTFALFTQ VVSHPLLRRA SVILFLNKID LLEKKLRQGR SLASFWPEYG GDNDFEAVWR
WFRAKFRDEL RRAEDDGGGA RRRLYVHTTV ATSTRQIKAI LMSVKDSILR DNLQAAGLV
//
