ID M9M5W4_PSEA3 Unreviewed; 1438 AA.
AC M9M5W4;
DT 29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 29-MAY-2013, sequence version 1.
DT 22-FEB-2023, entry version 42.
DE RecName: Full=Clustered mitochondria protein homolog {ECO:0000256|HAMAP-Rule:MF_03013};
DE AltName: Full=Protein TIF31 homolog {ECO:0000256|HAMAP-Rule:MF_03013};
GN Name=CLU1 {ECO:0000256|HAMAP-Rule:MF_03013};
GN Synonyms=TIF31 {ECO:0000256|HAMAP-Rule:MF_03013};
GN ORFNames=PANT_19d00057 {ECO:0000313|EMBL:GAC75995.1};
OS Pseudozyma antarctica (strain T-34) (Yeast) (Candida antarctica).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Moesziomyces.
OX NCBI_TaxID=1151754 {ECO:0000313|EMBL:GAC75995.1, ECO:0000313|Proteomes:UP000011976};
RN [1] {ECO:0000313|Proteomes:UP000011976}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T-34 {ECO:0000313|Proteomes:UP000011976};
RX PubMed=23558529; DOI=10.1128/genomea.00064-13;
RA Morita T., Koike H., Koyama Y., Hagiwara H., Ito E., Fukuoka T., Imura T.,
RA Machida M., Kitamoto D.;
RT "Genome sequence of the basidiomycetous yeast Pseudozyma antarctica T-34, a
RT producer of the glycolipid biosurfactants mannosylerythritol lipids.";
RL Genome Announc. 1:E0006413-E0006413(2013).
CC -!- FUNCTION: mRNA-binding protein involved in proper cytoplasmic
CC distribution of mitochondria. {ECO:0000256|HAMAP-Rule:MF_03013}.
CC -!- SUBUNIT: May associate with the eukaryotic translation initiation
CC factor 3 (eIF-3) complex. {ECO:0000256|HAMAP-Rule:MF_03013}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03013}.
CC -!- SIMILARITY: Belongs to the CLU family. {ECO:0000256|HAMAP-
CC Rule:MF_03013}.
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DR EMBL; DF196785; GAC75995.1; -; Genomic_DNA.
DR STRING; 1151754.M9M5W4; -.
DR OrthoDB; 927222at2759; -.
DR Proteomes; UP000011976; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007005; P:mitochondrion organization; IEA:UniProtKB-UniRule.
DR CDD; cd15466; CLU-central; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR HAMAP; MF_03013; CLU; 1.
DR InterPro; IPR033646; CLU-central.
DR InterPro; IPR025697; CLU_dom.
DR InterPro; IPR027523; CLU_prot.
DR InterPro; IPR023231; GSKIP_dom_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR12601:SF6; CLUSTERED MITOCHONDRIA PROTEIN HOMOLOG; 1.
DR PANTHER; PTHR12601; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3; 1.
DR Pfam; PF13236; CLU; 1.
DR Pfam; PF12807; eIF3_p135; 1.
DR Pfam; PF13374; TPR_10; 2.
DR Pfam; PF13424; TPR_12; 1.
DR SUPFAM; SSF103107; Hypothetical protein c14orf129, hspc210; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51823; CLU; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_03013};
KW Reference proteome {ECO:0000313|Proteomes:UP000011976};
KW RNA-binding {ECO:0000256|HAMAP-Rule:MF_03013}.
FT DOMAIN 361..657
FT /note="Clu"
FT /evidence="ECO:0000259|PROSITE:PS51823"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 178..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 533..578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 715..754
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1013..1067
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1411..1438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 533..570
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1414..1428
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1438 AA; 156297 MW; 7993B51547E5065A CRC64;
MAQEQPAEAP SQPPAAEVPE LDESLQPFDI NLYLPKRPLI PSAAASQNGL PETPSPLKVA
VTPQETLNDL RVTITDSPEG YWLGAFCFRK PQPGAAPTAK GAKVALGERV SEWTELREVF
QDVPKDQREL YVTHVPFNEA DARAHVQRLR DLLSGGAADP SAIGVDAALS VQDAVRNPEE
WQHDSSRQNA NGRNASKKGA DATAEAASTE SQLPFIDWAG WPAVTAIDLI PAVARRPRQL
PLCLRQLSLA SWNPPPQHCK LNGHLLYLQV GTLEGEVIFI TASTHGFYVN KSSGARFDPS
PRASGQDFAS CSLFDLLCGF SPLFLASFAR LFNDPLSSRD YFSAVPVTNS LPAIPWLARQ
HPHNPDPLRS QAAFLLTGAS SADTLEGTRD WNDELQSARE LPRTTLPERL MRDRVLNRIY
SEFTQAAARA IPKVAAGEVQ AMNPMDKRDA QMFIVNNLFI SKGADGVDLY PHMGGDEAAH
VAVGKDIQGV KTLNSLDVSG LCLLGTIVVD WKGERWVAQS VVPGLFRRRD DADAELEDGD
ANKAQETEAA KEEPKAENPT DDKAAAAKSP RGDLNDDTQV VYGGVEGPEV IRDNAAFHKL
FRQVAQTLHL SEHDVEDANG RTHPLWLSVD SKGLRGADGR RYVLDLARLN PVDINWLEKD
IAGAIHGSES SSSSDDKARY PHRMTLLRPE LLEIYWDSEF RKWARAKLAE RQEAKAAKAS
EAKAVEGKED AKEEGADADK AEAEAEEEPE RLDSSEFKLT FNPDAFVEFK VADPSVEDGS
KVITPITDES DASIAAVRQA SDFLRKVAIP RFVTDVAAGL FTAADGGALS RQMHARGINI
RYLGYVARLC APEAKSELDQ ELISKAGPGH EGFLHAFRST VLHEMVLRAS KRVLRGLVRD
VEQVNVAACV SHFLNCLVGD KVNAAPQSQP TSSPLSDASE AEWTQLTPES LKQKLVEEIR
KRYRFELPLS FFDQELRRPQ LLREVALRAG VQLKLQNYVL EGKLVEADGA LSDDSHGEVQ
ANGNAKENGA GVSGKKNKNK KKGSNGELNG SKKTAGSADK KPIQAARTTS FEPSDVLNLV
PVVKDSTPKS TLAEEAFDAG RLSISRGDRD LGLELLLEGV SFHEQVYGLV HPEVARCYAL
FATIVHHLAG VAAMERAEIL NQAKAENKEV SEADLPAVNE QVSMANAVRY QRQAVTVSER
TLGLDHPETL NQYMNLAVLE RSAGNTRESL LCQRRVLELW SLLYGQEHPD CINVLSNVAL
TLQNAKLFEA SLRVYESAHQ LALRLFGADS IHTANLAHEL SQAHTLVGDL KTALTVEKEA
WRVFEARLGK EDAQTKESET FCLNLAASAV RVAKLEKEAS AREARQGAFG LPNARRVGAN
ATANGAATTG AIAGAAPGGA PANANKSLDE IVRFIQGGSS TPSSTKGKSK GKGKAGRR
//
