ID   M9MBN0_PSEA3            Unreviewed;      1496 AA.
AC   M9MBN0;
DT   29-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE            EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN   ORFNames=PANT_7c00227 {ECO:0000313|EMBL:GAC72698.1};
OS   Pseudozyma antarctica (strain T-34) (Yeast) (Candida antarctica).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Moesziomyces.
OX   NCBI_TaxID=1151754 {ECO:0000313|EMBL:GAC72698.1, ECO:0000313|Proteomes:UP000011976};
RN   [1] {ECO:0000313|Proteomes:UP000011976}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=T-34 {ECO:0000313|Proteomes:UP000011976};
RX   PubMed=23558529; DOI=10.1128/genomea.00064-13;
RA   Morita T., Koike H., Koyama Y., Hagiwara H., Ito E., Fukuoka T., Imura T.,
RA   Machida M., Kitamoto D.;
RT   "Genome sequence of the basidiomycetous yeast Pseudozyma antarctica T-34, a
RT   producer of the glycolipid biosurfactants mannosylerythritol lipids.";
RL   Genome Announc. 1:E0006413-E0006413(2013).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC         ECO:0000256|RuleBase:RU363098};
CC   -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC       ECO:0000256|RuleBase:RU363098}.
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DR   EMBL; DF196773; GAC72698.1; -; Genomic_DNA.
DR   STRING; 1151754.M9MBN0; -.
DR   OrthoDB; 5477883at2759; -.
DR   Proteomes; UP000011976; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProt.
DR   InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR   PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   PANTHER; PTHR23079:SF17; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   Pfam; PF05183; RdRP; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011976};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW   ECO:0000256|RuleBase:RU363098};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
FT   REGION          990..1020
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1057..1078
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1244..1376
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1437..1458
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1004..1020
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1244..1270
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1312..1361
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1496 AA;  165381 MW;  72DF38E1EBDF473E CRC64;
     MEVFIDNIPH NLDAGAIERF IYAVVHTEQV FGSGARPLPG ISTPPAPPTT TAIVSINKGF
     FFKLVKRREG FHLGFLTFAR RKVALWFIEY AQWQPFVSRH GLRVRESREE PLPAFISAIA
     ENATDQQPSA SVQRAPPKYY FGVAHVGYWG APFRFNYTHA YVGGRLYLSI EDKNVIRIQL
     NHDVVTFLPR DVKTLTLRQV KSAGSTASDV GCIMFFELKS NPHIEGDLLR GDDAHAFRLP
     TRIIQLIFAK DKRASEDSKN LWKRLEVLLA GVPQLKYSKI QTYHDKNAPF VAKFFQRSKS
     LDVELALLRE SLLRNELLNM SALVKLSPKL DHMINQERGV DEEAVLRVSQ KLWDEACAEA
     TGNDSRGFLS VLDPTPSPDD DYLSKTFSID VTPTRVLLSG PHTHVSNRVI RAYSDHWHHF
     ARVTFSNEDR GGATTIKANY GFVESERYIQ SRVLKILQRG INVAGRHWEM LAWSSSSMSA
     HTVWFVTPFR DKDGTHVHAE VIRRELGDFT DVARYPAMYG ARLSQAFSAT ARTVEVDSSL
     ILHMPDIETP DRKMAYTDGV GQISPELMAE VWEKYVTSAL GEPRKRKFFK AAAPSAIQIR
     IGGHKGCLTV NPRLQGKQLA LRPSMSKFVS PHQDLEVANS SARCLSAKLN RPLINALDDR
     GVPATALLDI QKEAIAHIGR ARTHFDETAK LCSAYSFGTG CDLHILFQKL HKHGMGATSI
     HSDSFFLVLA KAVIAAALGD MKRKARIPVR GVTLIGVADE FAFLKEGEVF AQVEHVDLGQ
     VRRRVLVGTK LIGRSPTVDP GDIAMVKCVR PPPGHPLLQL RNVVVFNTCT RQEPLPRRLG
     GGDLDGDLYT IYEDERLFLP TPQPGTTFHA KTRPMELDRY CNSTDLANFF ADFMLNDFIG
     LVSHMHLRIA DASKAGSLDG RCKQLAMLHS LATDFRKTGV AVKRTQLPRM DEPIIPDFLA
     QGEPRQGGLT YPSTRVLGYL YRAVSWNQTD TPSLDKNTDP ETGLEPDYTE DYGDEDDLTS
     EIDSEFGSDF DSLVEQHVPQ GAARNPSARA TVGSAIGNRT LGSGQNGAND GNSASAQAAP
     WQFKDSTFPD LLERIANSNS DWLPTSPSDA DTDEQTVVEE GYRYVSLFIE FTRRLRSLSR
     MIAEYHPENN GSANGIGGAL LVSEVHLLTG RLPWAKVARK TCHDRDSKVL DSMQPLCALL
     RKNICRISEA EAFAPPVKRE DVKVEADVQP VAFTGIVSVA AKGASGSQQT RVQSGAAGGT
     GPTSGAASDY GSHRNPIEID SDSDSDSDAS DDVTVIGSRR GSFGPIGSQP RRPLVSVTNV
     VPPSSQASEA GSKRKASQDL PFTRSPRFSS KSSSHDSSST RNAATVEEEE EAEEGEFTVV
     SAQKVVDSLW RACCFFASPH RPRYSNVYGY NTFMITLVLH LLSMIETLKH LQRNTMRRTG
     RQPARPAQTT QTQVQWDGAA SEAYTEDDYS LTEDAVSALT LGTMLMDLSH TNAGYD
//