ID M9RH06_9RHOB Unreviewed; 819 AA.
AC M9RH06;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE SubName: Full=Sarcosine dehydrogenase {ECO:0000313|EMBL:AGI69691.1};
DE EC=1.5.8.3 {ECO:0000313|EMBL:AGI69691.1};
GN Name=sardh2 {ECO:0000313|EMBL:AGI69691.1};
GN ORFNames=OAN307_c43050 {ECO:0000313|EMBL:AGI69691.1};
OS Octadecabacter antarcticus 307.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Octadecabacter.
OX NCBI_TaxID=391626 {ECO:0000313|EMBL:AGI69691.1, ECO:0000313|Proteomes:UP000005307};
RN [1] {ECO:0000313|EMBL:AGI69691.1, ECO:0000313|Proteomes:UP000005307}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=307 {ECO:0000313|EMBL:AGI69691.1,
RC ECO:0000313|Proteomes:UP000005307};
RX PubMed=23671678;
RA Vollmers J., Voget S., Dietrich S., Gollnow K., Smits M., Meyer K.,
RA Brinkhoff T., Simon M., Daniel R.;
RT "Poles Apart: Arctic and Antarctic Octadecabacter strains Share High Genome
RT Plasticity and a New Type of Xanthorhodopsin.";
RL PLoS ONE 8:E63422-E63422(2013).
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
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DR EMBL; CP003740; AGI69691.1; -; Genomic_DNA.
DR RefSeq; WP_015501611.1; NC_020911.1.
DR AlphaFoldDB; M9RH06; -.
DR STRING; 391626.OAN307_c43050; -.
DR KEGG; oat:OAN307_c43050; -.
DR eggNOG; COG0404; Bacteria.
DR eggNOG; COG0665; Bacteria.
DR HOGENOM; CLU_007884_11_0_5; -.
DR OrthoDB; 7156675at2; -.
DR Proteomes; UP000005307; Chromosome.
DR GO; GO:0008480; F:sarcosine dehydrogenase activity; IEA:UniProtKB-EC.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR13847:SF193; PYRUVATE DEHYDROGENASE PHOSPHATASE REGULATORY SUBUNIT, MITOCHONDRIAL; 1.
DR PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:AGI69691.1}.
FT DOMAIN 12..368
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 372..426
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 428..701
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 728..811
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 819 AA; 89985 MW; 249F5A776E6F7AB3 CRC64;
MIQDLPTHVQ TVIVGGGSIG CNTAYHLTKL GHTDVLLLER DKLTSGTTWH AAGLVVAGIL
KSEAECEIYT HGRKLYAELE AETGLSTGFR DVGYLQIASN EERVHELRRI APFMRHHGIN
LHEISPTQTA ELFPIADLSD VKAGFYIPED GRANPVDLTM SLAKGARMGG ARITENVTVI
EILTKNGAAT GVRTSDGQTI TCENVVICGG MWSRQLGAAA GINLPLQAAE HYYLITDNIP
DLPRNLPVLE DPSTYTYYRE EVGGLMLGLF EPGAAAWNLD RIPDSFAFGE IEPDWDRVGP
HLERAYSRVP TAMDVGVRKL FCGPESFTPD LAPLVGETPE LRNCFVACGM NSLGILNGAG
TGMVLAHWIV AGMPPIDVTA INVNRFTRSE ATRAYRCDRT PELLGKLFGQ HYPNEPPKTA
RNVKRSVLHD RLADAGAYFT ESSGWETPDW FAPTPQQAKI ETHSWFREHW WDWHAQEHRA
AREDVIVMDM STMSKFMVEG RDACAVLNRL SCNDVDVAVG RVVYTAWTNE RGGFEADLTV
TRLTQDRFMV VVGENSHGHT EMRLRRTIGA DEQVIVFDAT AGITQINVHG PKARMLMEKL
TTADMSNDAF PFMSAQEIDV GYSVVWAYRV TFVGELGWEL HVPATQAAQV YDLIVDSGRD
FGLRNAGMQT LNSLRLEKAY RDFGLDVDNT DNPIEAGLGF AVKLDKPNGF IGRDALAAIK
DRGVPKTRML QFLLKDPESL LHGAEMIYLN GDVVGYLQVG GYGHSLGGAV GIGFVTLDKP
LTAQIVENGI WHVEIAGEQV SATASLKPLY DPTMSKVKS
//
