ID   M9THE4_DROME            Unreviewed;       319 AA.
AC   M9THE4;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   SubName: Full=FI19702p1 {ECO:0000313|EMBL:AGJ51083.1};
DE   Flags: Fragment;
GN   Name=Rrp4-RA {ECO:0000313|EMBL:AGJ51083.1};
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227 {ECO:0000313|EMBL:AGJ51083.1};
RN   [1] {ECO:0000313|EMBL:AGJ51083.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Carlson J., Booth B., Frise E., Park S., Wan K., Yu C., Celniker S.;
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the RRP4 family.
CC       {ECO:0000256|ARBA:ARBA00009155}.
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DR   EMBL; BT150044; AGJ51083.1; -; mRNA.
DR   AlphaFoldDB; M9THE4; -.
DR   EnsemblMetazoa; FBtr0343267; FBpp0309932; FBgn0034879.
DR   VEuPathDB; VectorBase:FBgn0034879; -.
DR   HOGENOM; CLU_034114_3_0_1; -.
DR   Bgee; FBgn0034879; Expressed in adult abdomen and 22 other cell types or tissues.
DR   ExpressionAtlas; M9THE4; baseline and differential.
DR   GO; GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:UniProt.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR   CDD; cd22525; KH-I_Rrp4_eukar; 1.
DR   CDD; cd05789; S1_Rrp4; 1.
DR   Gene3D; 2.40.50.100; -; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   InterPro; IPR025721; Exosome_cplx_N_dom.
DR   InterPro; IPR026699; Exosome_RNA_bind1/RRP40/RRP4.
DR   InterPro; IPR004088; KH_dom_type_1.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR048565; RRP4_S1.
DR   PANTHER; PTHR21321:SF4; EXOSOME COMPLEX COMPONENT RRP4; 1.
DR   PANTHER; PTHR21321; PNAS-3 RELATED; 1.
DR   Pfam; PF14382; ECR1_N; 1.
DR   Pfam; PF15985; KH_6; 1.
DR   Pfam; PF21266; RRP4_S1; 1.
DR   SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   SUPFAM; SSF110324; Ribosomal L27 protein-like; 1.
PE   2: Evidence at transcript level;
KW   Exosome {ECO:0000256|ARBA:ARBA00022835};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW   rRNA processing {ECO:0000256|ARBA:ARBA00022552}.
FT   DOMAIN          51..87
FT                   /note="Exosome complex component N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14382"
FT   DOMAIN          99..171
FT                   /note="RRP4 S1"
FT                   /evidence="ECO:0000259|Pfam:PF21266"
FT   DOMAIN          193..233
FT                   /note="K Homology"
FT                   /evidence="ECO:0000259|Pfam:PF15985"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AGJ51083.1"
SQ   SEQUENCE   319 AA;  36099 MW;  7AADB668E2F6062D CRC64;
     LLLFLPRSKL NFCLPRFGQT EMSTNAAIDL ALDRVDWRDL AAQTEEQPRV YTPGEVLMPE
     AGFMRGHGTF VEDENIKSSV AGVIQKVNKL ISVRPLKSRY VGEIGDVVVA RVSEVQQKRW
     RVDTNSRLDS ILLLSSVNLP GGELRRRSAE DEQMMRRYLD EGDLISAEVQ NIFEEGSLSL
     YTRSLKYGKL SQGILVKVFP ALVKRRKMHF HNLPCGASVI LGNNGYIWIS PTKGQEEEGG
     EGGFAQNLNE HVPRADREVI ARLRNSILAL AKCKLMIYDT SIQYAYEESL RYEAHELLQQ
     NAIYDIGQQT QARLRDADE
//