ID M9WH48_9MOLU Unreviewed; 230 AA.
AC M9WH48;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN Name=dam {ECO:0000313|EMBL:AGJ90714.1};
GN ORFNames=MPUT9231_2900 {ECO:0000313|EMBL:AGJ90714.1};
OS Mycoplasma putrefaciens Mput9231.
OC Bacteria; Mycoplasmatota; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=1292033 {ECO:0000313|EMBL:AGJ90714.1, ECO:0000313|Proteomes:UP000012984};
RN [1] {ECO:0000313|EMBL:AGJ90714.1, ECO:0000313|Proteomes:UP000012984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mput9231 {ECO:0000313|EMBL:AGJ90714.1};
RX PubMed=23766410;
RA Dupuy V., Sirand-Pugnet P., Baranowski E., Barre A., Breton M., Couture C.,
RA Dordet-Frisoni E., Gaurivaud P., Jacob D., Lemaitre C., Manso-Silvan L.,
RA Nikolski M., Nouvel L.X., Poumarat F., Tardy F., Thebault P., Theil S.,
RA Citti C., Blanchard A., Thiaucourt F.;
RT "Complete Genome Sequence of Mycoplasma putrefaciens Strain 9231, One of
RT the Agents of Contagious Agalactia in Goats.";
RL Genome Announc. 1:e00354-13(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC Evidence={ECO:0000256|ARBA:ARBA00001279};
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594}.
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DR EMBL; CP004357; AGJ90714.1; -; Genomic_DNA.
DR RefSeq; WP_015587332.1; NC_021083.1.
DR AlphaFoldDB; M9WH48; -.
DR KEGG; mput:MPUT9231_2900; -.
DR PATRIC; fig|1292033.3.peg.282; -.
DR eggNOG; COG0338; Bacteria.
DR HOGENOM; CLU_1282035_0_0_14; -.
DR OrthoDB; 9805629at2; -.
DR Proteomes; UP000012984; Chromosome.
DR GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR012327; MeTrfase_D12.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR30481; DNA ADENINE METHYLASE; 1.
DR PANTHER; PTHR30481:SF3; DNA ADENINE METHYLASE; 1.
DR Pfam; PF02086; MethyltransfD12; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:AGJ90714.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000012984};
KW Transferase {ECO:0000313|EMBL:AGJ90714.1}.
SQ SEQUENCE 230 AA; 27119 MW; 1CF11D2AC94A5520 CRC64;
MISKQNLKKV SPVISYYGSK FRLLDKIFSL LDLQENDIFL DLFGGSGIVG VNAKEIFNCK
VIINDYDRIL PLDIEYALRN VLSFEGNCKN YTIARWKYFL KRLDNKWVDK FYKYNDILKR
VRITSYDYQT ILNKIIDNTN TNLKPTKIYV DPPYFNKKGL YKSSFNDEQH IKLFKLLEIL
KPFSRIVISY NDSVFIRKLY SNWKIIEITK TNTSGIVKTK NVTELLITNV
//
