ID M9ZQC1_9PLEU Unreviewed; 242 AA.
AC M9ZQC1;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=ubiquitinyl hydrolase 1 {ECO:0000256|ARBA:ARBA00012759};
DE EC=3.4.19.12 {ECO:0000256|ARBA:ARBA00012759};
DE Flags: Fragment;
GN Name=VCPIP {ECO:0000313|EMBL:AGK35290.1};
OS Trichopsetta ventralis (sash flounder).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Carangaria; Pleuronectiformes; Pleuronectoidei; Bothidae; Trichopsetta.
OX NCBI_TaxID=1286178 {ECO:0000313|EMBL:AGK35290.1};
RN [1] {ECO:0000313|EMBL:AGK35290.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=E0599 {ECO:0000313|EMBL:AGK35290.1};
RG Euteleost Tree of Life Consortium;
RA Betancur R.-R., Broughton R.E., Wiley E.O., Carpenter K., Lopez J.A.,
RA Li C., Holcroft N.I., Arcila D., Sanciangco M., Cureton J.C.II., Zhang F.,
RA Buser T., Campbell M.A., Ballesteros J.A., Roa-Varon A., Willis S.,
RA Borden W.C., Rowley T., Reneau P.C., Hough D.J., Lu G., Grande T.,
RA Arratia G., Orti G.;
RT "The Tree of Life and a New Classification of Bony Fishes.";
RL PLoS Curr 1:1-45(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Thiol-dependent hydrolysis of ester, thioester, amide, peptide
CC and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-
CC residue protein attached to proteins as an intracellular targeting
CC signal).; EC=3.4.19.12; Evidence={ECO:0000256|ARBA:ARBA00000707};
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DR EMBL; KC830584; AGK35290.1; -; Genomic_DNA.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd22769; OTU_VCIP135; 1.
DR Gene3D; 3.90.70.80; -; 1.
DR InterPro; IPR003323; OTU_dom.
DR InterPro; IPR039087; VCPIP1.
DR InterPro; IPR045827; VCPIP1_N.
DR PANTHER; PTHR14843; DEUBIQUITINATING PROTEIN VCIP135; 1.
DR PANTHER; PTHR14843:SF2; DEUBIQUITINATING PROTEIN VCPIP1; 1.
DR Pfam; PF02338; OTU; 1.
DR Pfam; PF19437; VCIP135_N; 1.
DR PROSITE; PS50802; OTU; 1.
PE 4: Predicted;
FT DOMAIN 121..238
FT /note="OTU"
FT /evidence="ECO:0000259|PROSITE:PS50802"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AGK35290.1"
FT NON_TER 242
FT /evidence="ECO:0000313|EMBL:AGK35290.1"
SQ SEQUENCE 242 AA; 26974 MW; 15C2489C94C69D2E CRC64;
VTDPDVXLHN LLRNALLGVT GAPKKGTELV KVMGLSNYHC KLLSPVLTRY GMDKQTGKAK
LLRDMNQGEM FDCSLLGDRA FLMEPDHVST MGYGKDRSGS LIYLHDTLEE VKKANGNREC
LIPVHVDGDG HCLVHAVSRA LVGRELFWHA LRENLKQNFK KNLERYKALF QDFIDAAEWE
DIINECDPLF VPPEGVPLGL RNIHIFGLAN VLHRPIILLD SLSGMRSSGD YSATFLPGLV
AE
//
