ID MDCF_RHIME Reviewed; 320 AA.
AC P56949;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2000, sequence version 1.
DT 27-MAR-2024, entry version 105.
DE RecName: Full=Putative malonate transporter;
GN Name=mdcF; OrderedLocusNames=R01674; ORFNames=SMc00317;
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=10858449; DOI=10.1074/jbc.m000844200;
RA Sohlenkamp C., de Rudder K.E.E., Roehrs V., Lopez-Lara I.M., Geiger O.;
RT "Cloning and characterization of the gene for phosphatidylcholine
RT synthase.";
RL J. Biol. Chem. 275:18919-18925(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11481430; DOI=10.1073/pnas.161294398;
RA Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT meliloti strain 1021.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the auxin efflux carrier (TC 2.A.69) family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF155772; AAF27308.1; -; Genomic_DNA.
DR EMBL; AL591688; CAC46253.1; -; Genomic_DNA.
DR RefSeq; NP_385780.1; NC_003047.1.
DR RefSeq; WP_003533213.1; NC_003047.1.
DR AlphaFoldDB; P56949; -.
DR SMR; P56949; -.
DR TCDB; 2.A.69.3.4; the auxin efflux carrier (aec) family.
DR EnsemblBacteria; CAC46253; CAC46253; SMc00317.
DR GeneID; 61603143; -.
DR KEGG; sme:SMc00317; -.
DR PATRIC; fig|266834.11.peg.3107; -.
DR eggNOG; COG0679; Bacteria.
DR HOGENOM; CLU_056175_2_1_5; -.
DR OrthoDB; 7329340at2; -.
DR Proteomes; UP000001976; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR004776; Mem_transp_PIN-like.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR36838; AUXIN EFFLUX CARRIER FAMILY PROTEIN; 1.
DR PANTHER; PTHR36838:SF1; SLR1864 PROTEIN; 1.
DR Pfam; PF03547; Mem_trans; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..320
FT /note="Putative malonate transporter"
FT /id="PRO_0000123797"
FT TRANSMEM 1..21
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 32..52
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 167..187
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 256..276
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 289..309
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 320 AA; 34020 MW; 173DAFCA22E11959 CRC64;
MAEITGLVLP FFGLIFLGYL TARLVDHPGE AMGWLNTFIV YLALPALFFK LVSRTPVEEL
TRADFILTSV GTTYVVFALI FAIGLFLRRN TVAEATMQGF AGAYGNIGYM GPGLALLALG
ETAAVPVALI FCFENAAHFT VAPAMMAAAG GSKQKPAVVA LGIARRIAFH PFILSTFAGV
AAAFLSFEPP LPLQRLIDYL AQAAAPCALF AMGVTLALRP LKRIPAEIGY IVPAKLVLHP
VLMYLALSLG GAYDPIWVQT AVLLASLPTA TNVFVIGQQY GVWQERASAT ILITTLLSVA
TVTGLLYLIR SGALPADLFP
//
