ID   MTG8R_XENLA             Reviewed;         586 AA.
AC   Q9IAB2;
DT   29-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 2.
DT   03-APR-2013, entry version 55.
DE   RecName: Full=Protein CBFA2T2;
DE   AltName: Full=MTG8-like protein;
DE   AltName: Full=MTG8-related protein 1;
GN   Name=cbfa2t2; Synonyms=mtgr1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus;
OC   Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Cao Y., Zhao H., Grunz H.;
RT   "A novel Xenopus gene homologous to human MTGR1.";
RL   Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus (By similarity).
CC   -!- SIMILARITY: Contains 1 MYND-type zinc finger.
CC   -!- SIMILARITY: Contains 1 TAFH (NHR1) domain.
CC   -!- CAUTION: It is uncertain whether Met-1 or Met-19 is the initiator.
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DR   EMBL; AF212198; AAF63193.2; -; mRNA.
DR   UniGene; Xl.4960; -.
DR   ProteinModelPortal; Q9IAB2; -.
DR   SMR; Q9IAB2; 101-206, 327-384, 492-540.
DR   Xenbase; XB-GENE-950038; cbfa2t2.
DR   HOVERGEN; HBG000169; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0050768; P:negative regulation of neurogenesis; IEP:UniProtKB.
DR   GO; GO:0010977; P:negative regulation of neuron projection development; ISS:UniProtKB.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-dependent; IEP:UniProtKB.
DR   InterPro; IPR013289; ETO.
DR   InterPro; IPR013291; MTGR1.
DR   InterPro; IPR014896; NHR2.
DR   InterPro; IPR003894; TAFH_NHR1.
DR   InterPro; IPR002893; Znf_MYND.
DR   Pfam; PF08788; NHR2; 1.
DR   Pfam; PF07531; TAFH; 1.
DR   Pfam; PF01753; zf-MYND; 1.
DR   PRINTS; PR01875; ETOFAMILY.
DR   PRINTS; PR01877; MTGR1PROTEIN.
DR   SMART; SM00549; TAFH; 1.
DR   PROSITE; PS51119; TAFH; 1.
DR   PROSITE; PS01360; ZF_MYND_1; 1.
DR   PROSITE; PS50865; ZF_MYND_2; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Metal-binding; Nucleus; Zinc; Zinc-finger.
FT   CHAIN         1    586       Protein CBFA2T2.
FT                                /FTId=PRO_0000218303.
FT   DOMAIN      102    197       TAFH.
FT   ZN_FING     497    533       MYND-type.
FT   COILED      429    481       Potential.
FT   COMPBIAS     84     90       Poly-Ser.
SQ   SEQUENCE   586 AA;  65055 MW;  7280D4C81F40F286 CRC64;
     MVGIPGPYQF TGDKRVPAMP GSPMEVKIHS RSSPPIMAPL PPVNPGGLRP VGFPPSSHSN
     GINHSPPTLN GAPSPPQRSS NGPSSSSSSS LANQQLPATC GVRQLSKLKR FLTTLQQFGN
     DISPEIGEKV RTLVLALVNS TVTIEEFHCK LQEATNFPLR PFVIPFLKAN LPLLQRELLH
     CARAGKQTPS QYLAQHEHIL LNTSTSSPAD SSELLMEMNG NGKRHSPDRR EEERETAPAE
     PPVKRVCTIS PAPRHSPALS LPLVNSTSHF HPTPPPLQHY SLEDIPSSQL YRDHLNKIGE
     HRDVRDRHHS SGVNGNLNNG YQEELVDHRL TEREWAEEWK HLDHALNCIM EMVEKTRRSM
     AVLRRCQEVD RDELNYWKRR FNESNEIRKG SEHPSRQHSP SSTDSGASDS VRDFGSRTGA
     GYVTDEIWRK AEEAVNEVKR QAMSEVQKAV SEAEQKAFEM IASERARMEQ TIVDAKRRAA
     EDAVLVVNEQ EESTESCWNC GRKASETCSG CNIARYCGSF CQHKDWEKHH RICGQSMHTQ
     AKPLTPSRSL IPKASDPVLL SPTLERSSSA TSRSSTPASV TAVDGL
//