ID   N0E147_9MICO            Unreviewed;      1171 AA.
AC   N0E147;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   RecName: Full=TM0106 family RecB-like nuclease {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BN10_630017 {ECO:0000313|EMBL:CCH70663.1};
OS   Phycicoccus elongatus Lp2.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC   Phycicoccus.
OX   NCBI_TaxID=1193181 {ECO:0000313|EMBL:CCH70663.1, ECO:0000313|Proteomes:UP000013167};
RN   [1] {ECO:0000313|EMBL:CCH70663.1, ECO:0000313|Proteomes:UP000013167}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lp2 {ECO:0000313|EMBL:CCH70663.1,
RC   ECO:0000313|Proteomes:UP000013167};
RX   PubMed=23178666; DOI=10.1038/ismej.2012.136;
RA   Kristiansen R., Nguyen H.T.T., Saunders A.M., Nielsen J.L., Wimmer R.,
RA   Le V.Q., McIlroy S.J., Petrovski S., Seviour R.J., Calteau A.,
RA   Nielsen K.L., Nielsen P.H.;
RT   "A metabolic model for members of the genus Tetrasphaera involved in
RT   enhanced biological phosphorus removal.";
RL   ISME J. 7:543-554(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCH70663.1}.
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DR   EMBL; CAIZ01000134; CCH70663.1; -; Genomic_DNA.
DR   RefSeq; WP_010850506.1; NZ_HF570956.1.
DR   AlphaFoldDB; N0E147; -.
DR   STRING; 1193181.BN10_630017; -.
DR   eggNOG; COG1112; Bacteria.
DR   eggNOG; COG2251; Bacteria.
DR   HOGENOM; CLU_008884_0_0_11; -.
DR   OrthoDB; 9757917at2; -.
DR   Proteomes; UP000013167; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd17934; DEXXQc_Upf1-like; 1.
DR   CDD; cd18808; SF1_C_Upf1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR019993; RecB_nuclease_TM0106_put.
DR   InterPro; IPR047187; SF1_C_Upf1.
DR   InterPro; IPR038720; YprB_RNase_H-like_dom.
DR   NCBIfam; TIGR03491; TM0106 family RecB-like putative nuclease; 1.
DR   PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR43788:SF6; RECBCD ENZYME SUBUNIT RECD; 1.
DR   Pfam; PF13087; AAA_12; 1.
DR   Pfam; PF13604; AAA_30; 1.
DR   Pfam; PF13482; RNase_H_2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000013167}.
FT   DOMAIN          316..506
FT                   /note="YprB ribonuclease H-like"
FT                   /evidence="ECO:0000259|Pfam:PF13482"
FT   DOMAIN          960..1138
FT                   /note="DNA2/NAM7 helicase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13087"
SQ   SEQUENCE   1171 AA;  127217 MW;  D44E985F2DCE99FC CRC64;
     MFLLGDRLVT SPSDLRLAAT CEFALVRTLD ATLGRIAGLP VTDDAMLARV AELGTQHEQR
     ELLRLSARHP GRVLQFPRPA YTLEGLTTAH ETTLATLRGD SADVVVQATF FDGGFVGHSD
     FLERTDDGWL VMDAKLARSE SVPALLQIGA YAACLTEAGI PTAPIARLVL GTGEPSDHPL
     NDLLPVHRAR RARLAAVMEA HAADDGPALW RDDRWLACGR CEVCVAAAEE TRDVLLVAGV
     RMPTRRRLLE AGVHTVEDLA ARTEPVPEVR AATFERLVAQ ARLQVEQDGD PTGRVRSEVV
     STAALATIPE PSAGDVFFDF EGDPLWAERG SSDWGLEYLF GLIEIDTGTP EFRTFWAHDR
     EAEKQALIDF VTYVQQRRRQ WPTMHVHHYA NYEVVALLRL AVRHGVCEEE IDQFLREGVF
     VDLYAVVRAG VRVSQRSYSI KKLEPLYMDK RAIALQSGGD SITVYHEFCA ARDRGDEAEA
     HRLLELIHDY NRDDCLSTLG LRDWLVQQRE ASPVVEPASD DVGEGAPAGP VSLSADRQAR
     IALEQALREL IADTKPHERT AEQQAIALAA AAVQFHARED KPFWWRHFGR LRTPVADWPA
     DSGVFVVQEA TVVTDWHRQS SRQKPRRILR LVGEPLSGTL LTPRDEVNAV YAAPGPAGIP
     MERGFHHGKS PAGVRILEAS PALTTGGHVR QELVVEELMP TGGEEHAPIP AGLVPGGLVR
     VDNIDAAITD FAAELHAQWP AVPARAGADL LLRRPPRFRR GTALPAAAEG DQVATITAAL
     LDLDNSYLAV QGPPGTGKTH VASHVIAALV QHGWRIGVCA QSHAAIENVL AAVIRAGVPA
     GQVAKRTVEA EHPAWTDLAQ ADDLATFARD HEGGYVIGGT AWDLTNPKRV ERDQLDLVVV
     DEAGQFSLAK TMAVAMAGAR LLLLGDPQQL PQVSQGSHPD PVDLSALGWL IGEEPVLDPE
     HGYFLATTWR MHPALTAPVS RLSYAGQLHS QVSVTQSRSL DGVEPGLHVR SVDHHDNRSS
     SPEEAAAVVD LVRDMIGRRW IPAVEDGEPE RAIGPQDVII TTPYNAQVAT IRAALDAAGF
     DEVPVGTVDK FQGREAPVAI VSMAASSPSD VSRGIDFLLD RNRLNVAISR AKHAAYLVRS
     PLLTDLAPRS PRELVALGAF IGLCERAVTT T
//