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Database: UniProt
Entry: N1MKI2_9SPHN
LinkDB: N1MKI2_9SPHN
Original site: N1MKI2_9SPHN 
ID   N1MKI2_9SPHN            Unreviewed;       460 AA.
AC   N1MKI2;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   05-JUL-2017, entry version 29.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=EBBID32_20790 {ECO:0000313|EMBL:CCW17730.1};
OS   Sphingobium japonicum BiD32.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingobium.
OX   NCBI_TaxID=1301087 {ECO:0000313|EMBL:CCW17730.1, ECO:0000313|Proteomes:UP000013201};
RN   [1] {ECO:0000313|EMBL:CCW17730.1, ECO:0000313|Proteomes:UP000013201}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BiD32 {ECO:0000313|EMBL:CCW17730.1,
RC   ECO:0000313|Proteomes:UP000013201};
RA   Le V.;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CCW17730.1, ECO:0000313|Proteomes:UP000013201}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BiD32 {ECO:0000313|EMBL:CCW17730.1,
RC   ECO:0000313|Proteomes:UP000013201};
RA   Nielsen J.L., Zhou N.A., Kjeldal H.;
RT   "Bisphenol A degrading Sphingobium sp. strain BiD32.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:CCW17730.1}.
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DR   EMBL; CAVK010000096; CCW17730.1; -; Genomic_DNA.
DR   EnsemblBacteria; CCW17730; CCW17730; EBBID32_20790.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000013201; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000013201};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000013201}.
FT   DOMAIN      156    290       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      368    437       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     164    171       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   460 AA;  50362 MW;  3D88C52A4E7BE99D CRC64;
     MAGWQDGEGS QADSSLQAAW AGIRAGLRRD IGARMFDQWL KPVRLGDYCP ESQTLDLLVA
     TDFSANFVSG QFGDRLRMAW RAANIGVREV RLHRAPDATG PRLLEVVHVE PTVAPAPQPI
     ASNFLPRHGF ADFVTGDSNR LACSAALAMA GEAEPRFSPL FIHGGTGQGK THLLHAIARA
     FSDHAPAAPV LYMSAERFMM EFVNAMRANE TMAFKARLRA ARLLLIDDIQ FIAGKGSTQE
     EFLHTINYLI DSGARIVVTA DRPPQRLESI DARILSRLAG GLVADILPAD LDLRLAILEA
     KRAVAGDPPV PDAVIDFLAR SIRSNVRELE GAFNKLVAYG QLTGRAIDLD FAQGMLADAV
     RANARRITVD EIQKVCAAHY KIDASEMRSK RRARAVARPR QVAMYLAKKM TPRSLPEIGR
     IFGGRDHSTV IHAVRTIEGL RESNPDIDAD VRALLRQLEG
//
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