ID N1PCC1_DOTSN Unreviewed; 947 AA.
AC N1PCC1;
DT 26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT 26-JUN-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN ORFNames=DOTSEDRAFT_138071 {ECO:0000313|EMBL:EME40103.1};
OS Dothistroma septosporum (strain NZE10 / CBS 128990) (Red band needle blight
OS fungus) (Mycosphaerella pini).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Dothistroma.
OX NCBI_TaxID=675120 {ECO:0000313|EMBL:EME40103.1, ECO:0000313|Proteomes:UP000016933};
RN [1] {ECO:0000313|Proteomes:UP000016933}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NZE10 / CBS 128990 {ECO:0000313|Proteomes:UP000016933};
RX PubMed=23209441; DOI=10.1371/journal.pgen.1003088;
RA de Wit P.J.G.M., van der Burgt A., Oekmen B., Stergiopoulos I.,
RA Abd-Elsalam K.A., Aerts A.L., Bahkali A.H., Beenen H.G., Chettri P.,
RA Cox M.P., Datema E., de Vries R.P., Dhillon B., Ganley A.R.,
RA Griffiths S.A., Guo Y., Hamelin R.C., Henrissat B., Kabir M.S.,
RA Jashni M.K., Kema G., Klaubauf S., Lapidus A., Levasseur A., Lindquist E.,
RA Mehrabi R., Ohm R.A., Owen T.J., Salamov A., Schwelm A., Schijlen E.,
RA Sun H., van den Burg H.A., van Ham R.C.H.J., Zhang S., Goodwin S.B.,
RA Grigoriev I.V., Collemare J., Bradshaw R.E.;
RT "The genomes of the fungal plant pathogens Cladosporium fulvum and
RT Dothistroma septosporum reveal adaptation to different hosts and lifestyles
RT but also signatures of common ancestry.";
RL PLoS Genet. 8:E1003088-E1003088(2012).
RN [2] {ECO:0000313|EMBL:EME40103.1, ECO:0000313|Proteomes:UP000016933}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NZE10 / CBS 128990 {ECO:0000313|Proteomes:UP000016933};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC ECO:0000256|RuleBase:RU363098};
CC -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC ECO:0000256|RuleBase:RU363098}.
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DR EMBL; KB446544; EME40103.1; -; Genomic_DNA.
DR AlphaFoldDB; N1PCC1; -.
DR STRING; 675120.N1PCC1; -.
DR EnsemblFungi; EME40103; EME40103; DOTSEDRAFT_138071.
DR eggNOG; KOG0988; Eukaryota.
DR HOGENOM; CLU_001366_2_0_1; -.
DR OMA; VDEKKIW; -.
DR OrthoDB; 5477883at2759; -.
DR Proteomes; UP000016933; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProt.
DR InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR PANTHER; PTHR23079:SF17; RNA-DEPENDENT RNA POLYMERASE; 1.
DR Pfam; PF05183; RdRP; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW Reference proteome {ECO:0000313|Proteomes:UP000016933};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|RuleBase:RU363098};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW ECO:0000256|RuleBase:RU363098};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
SQ SEQUENCE 947 AA; 106757 MW; 7DEB0A9BED4E3BEA CRC64;
MCPVVAQKTT SQYPQQTLKE SFVKLNHELA DTKRFGRRPF GLRYQVDKLA RNGILAPGKV
LRLLPKIAQL HDSFGLDAAS AALGRLGRER VLPGPSEQAH DFSLARLEEL LESYAASYDT
TAPDNPYELS KRYAHINLVH KIIITPAGTY LEGPDAEPTN RVLRRYHHST DHFVRVIFQD
EDRSPMRHDP RTDQSQIYHM RFKGVLDGSV LICGRAFSFL GFSHSSLRSQ SCWFSAPMVS
KQGSLVFAEQ VIKELGDFSK IRVPAKCAAR IGQNFTDTNA SVKLRPEEVF ELPNVERNGR
DFSDGVGTIS ERLLQSVHRR YGSKKLLKPT ALQIRFQGSK GMVALDSRLP GKRLMIRPNM
KKYETAATWD LEICGAAFRP LPMVLNRPFI KVMEDLGTPI STFMDLQNAA MVHLQRMTAS
CINTAIFLDD SEACRATRMS ELIRYLGQIG LDYHHDHFMY SVVEMAVVAK LRDIKYKGRI
PVEQGVTLYG IMDETGYLGP REIYVVTEKA EGGKKVVVAN DIIVTRSPAL HPGDMQVVNA
VDVPQTSPLK RLSNVVVFSK HGDRDLPSQL GGGDLDGDLY NIIWDPKLRP MRTFQPADYP
RVSAVQLDRD VVRKDMSDFF VTFMESDVLG MICTTHLQLA DQRSAGVLDP DCIKLAGMAS
TAVDFSKTGI PVNIKDIPRY TRVKPDFMAP SPRVVVSDGG FLDFEEDDDG EDDAFEGLDT
ERRRTRFYRS EKALGHLYRA IDEGKFLHNM QNQNRQINSR PLQDDLLSVL LAYVKKWATQ
YGVLYDHHLT LAANIRSSYE DSLLSLLYDY EPSPHAPLFE AEIFSGQILG RQGGPQGKPL
REQSTQMRER FETVAEYACM RIVKGDEAMK TASNLDDLID LHYNEREIEA LPRALACFDV
AVRKEGLKDK RLGELRSFRY VAAGVCLREL DRYRITTFGR VGGLPSI
//
